Fragment‐based modeling of membrane protein loops: Successes, failures, and prospects for the future
Membrane proteins (MPs) have become a major focus in structure prediction, due to their
medical importance. There is, however, a lack of fast and reliable methods that specialize in …
medical importance. There is, however, a lack of fast and reliable methods that specialize in …
Large oligomeric complex structures can be computationally assembled by efficiently combining docked interfaces
M Dietzen, OV Kalinina, K Taškova… - Proteins: Structure …, 2015 - Wiley Online Library
Macromolecular oligomeric assemblies are involved in many biochemical processes of
living organisms. The benefits of such assemblies in crowded cellular environments include …
living organisms. The benefits of such assemblies in crowded cellular environments include …
Structural modelling of transmembrane domains
S Kelm - 2011 - ora.ox.ac.uk
Membrane proteins represent about one third of all known vertebrate proteins and over half
of the current drug targets. Knowledge of their three-dimensional (3D) structure is worth …
of the current drug targets. Knowledge of their three-dimensional (3D) structure is worth …