Amyloid diseases are global epidemics with profound health, social and economic
implications and yet remain without a cure. This dire situation calls for research into the …

Bacteria can form single-and multispecies biofilms exhibiting diverse features based upon
the microbial composition of their community and microenvironment. The study of bacterial …

In nature, bacteria primarily live in surface-attached, multicellular communities, termed
biofilms,,,,–. In medical settings, biofilms cause devastating damage during chronic and …

Morphological form in multicellular aggregates emerges from the interplay of genetic
constitution and environmental signals. Bacterial macrocolony biofilms, which form intricate …

Biofilms constitute the predominant microbial style of life in natural and engineered
ecosystems. Facing harsh environmental conditions, microorganisms accumulate reactive …

A variety of fascinating morphological patterns arise on surfaces of growing, developing or
aging tissues, organs and microorganism colonies. These patterns can be classified into …

Many bacteria assemble extracellular amyloid fibers on their cell surface. Secretion of
proteins across membranes and the assembly of complex macromolecular structures must …

Curli are extracellular functional amyloids that are assembled by enteric bacteria during
biofilm formation and host colonization. An efficient secretion system and chaperone …

Bacterial biofilms are ubiquitous in nature, and their resilience is derived in part from a
complex extracellular matrix that can be tailored to meet environmental demands. Although …

In natural habitats, bacteria often occur in multicellular communities characterized by a
robust extracellular matrix of proteins, amyloid fibres, exopolysaccharides and extracellular …