Adipokines in nonalcoholic fatty liver disease

SA Polyzos, J Kountouras, CS Mantzoros - Metabolism, 2016 - Elsevier
Since the discovery of adipose tissue as a higly active endocrine tissue, adipokines,
peptides produced by adipose tissue and exerting autocrine, paracrine and endocrine …

Circulating leptin in non-alcoholic fatty liver disease: a systematic review and meta-analysis

SA Polyzos, KN Aronis, J Kountouras, DD Raptis… - Diabetologia, 2016 - Springer
Aims/hypothesis Clinical data regarding circulating leptin levels in patients with non-
alcoholic fatty liver disease (NAFLD) are conflicting. The purpose of this meta-analysis was …

Fast food diet mouse: novel small animal model of NASH with ballooning, progressive fibrosis, and high physiological fidelity to the human condition

M Charlton, A Krishnan, K Viker… - American Journal …, 2011 - journals.physiology.org
Although there are small animal platforms that recapitulate some of the histological features
of nonalcoholic fatty liver disease, there are no small animal models of nonalcoholic …

[PDF][PDF] Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis: Selected practical issues in their evaluation and management

R Vuppalanchi, N Chalasani - Hepatology, 2009 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is among the most common causes of chronic liver
disease in the western world. It is now recognized that these patients have myriad of …

Leptin in nonalcoholic fatty liver disease: a narrative review

SA Polyzos, J Kountouras, CS Mantzoros - Metabolism, 2015 - Elsevier
Leptin, the first described adipokine, interplays with hepatic metabolism. The aim of this
review was to summarize available data on the association between leptin and nonalcoholic …

[HTML][HTML] Endocrine aspects of metabolic dysfunction associated steatotic liver disease (MASLD): Beyond insulin resistance

AL Hutchison, F Tavaglione, S Romeo, M Charlton - Journal of Hepatology, 2023 - Elsevier
While the links between metabolic dysfunction associated steatotic liver disease liver
disease (MASLD) and obesity, insulin resistance are widely appreciated, there are a host of …

Non-alcoholic fatty liver disease pathogenesis: the present and the future

S Petta, C Muratore, A Craxi - Digestive and Liver Disease, 2009 - Elsevier
Non-alcoholic fatty liver disease is the clinical hepatic expression of metabolic syndrome.
The prevalence of non-alcoholic fatty liver disease is around 20–30%, and with a rapid …

Practice guidelines for the diagnosis and management of nonalcoholic fatty liver disease: A decalogue from the Italian Association for the Study of the Liver (AISF) …

P Loria, LE Adinolfi, S Bellentani, E Bugianesi… - Digestive and Liver …, 2010 - Elsevier
We report the evidence-based Italian Association for the Study of Liver guidelines for the
appropriate diagnosis and management of patients with nonalcoholic fatty liver disease in …

Prevalence and factors associated with the presence of nonalcoholic fatty liver disease in an adult population in Spain

L Caballería, G Pera, MA Auladell… - European journal of …, 2010 - journals.lww.com
Background/aims The prevalence of nonalcoholic fatty liver disease (NAFLD) is unknown in
Spain. The purpose of detecting NAFLD patients is to determine the associated factors and …

Non-invasive diagnosis of non-alcoholic steatohepatitis by combined serum biomarkers

J Shen, HLY Chan, GLH Wong, PCL Choi… - Journal of …, 2012 - Elsevier
BACKGROUND & AIMS: The diagnosis of non-alcoholic fatty liver disease (NAFLD) and
steatohepatitis (NASH) is limited by the need for liver biopsy. We aimed at testing the …