The application of Interleukin-2 family cytokines in tumor immunotherapy research

Y Zhou, G Quan, Y Liu, N Shi, Y Wu, R Zhang… - Frontiers in …, 2023 - frontiersin.org
The Interleukin-2 Family contains six kinds of cytokines, namely IL-2, IL-15, IL-4, IL-7, IL-9,
and IL-21, all of which share a common γ chain. Many cytokines of the IL-2 family have been …

A novel inflammatory-related gene signature based model for risk stratification and prognosis prediction in lung adenocarcinoma

WY Zhai, FF Duan, S Chen, JY Wang, YB Lin… - Frontiers in …, 2022 - frontiersin.org
Inflammation is an important hallmark of cancer and plays a role in both neogenesis and
tumor development. Despite this, inflammatory-related genes (IRGs) remain to be poorly …

Characterizing influence of rCHOP treatment on diffuse large B-cell lymphoma microenvironment through in vitro microfluidic spheroid model

MR Sullivan, RP White, D Ravi, N Kanetkar… - Cell Death & …, 2024 - nature.com
For over two decades, Rituximab and CHOP combination treatment (rCHOP) has remained
the standard treatment approach for diffuse large B-cell lymphoma (DLBCL). Despite …

Microfluidic viscometer using a suspending micromembrane for measurement of biosamples

L Liu, D Hu, RHW Lam - Micromachines, 2020 - mdpi.com
The viscosity of biofluids such as blood and saliva can reflect an individual's health
conditions, and viscosity measurements are therefore considered in health monitoring and …

[HTML][HTML] A novel classification predicts prognosis and drug sensitivity in osteosarcoma based on alterations in gene sets

S Ye, X Wang, R Chen - Aging (Albany NY), 2024 - ncbi.nlm.nih.gov
Osteosarcoma is a cancer originating in the bone cells, specifically in the osteoblasts.
Previous studies mainly focused on particular molecules but the whole pathway network. We …

Local and systemic interleukin-32 in esophageal, gastric, and colorectal cancers: Clinical and diagnostic significance

D Diakowska, M Krzystek-Korpacka - Diagnostics, 2020 - mdpi.com
Little is known on clinical and diagnostic relevance of interleukin-32 in gastrointestinal tract
(GIT) cancers. We determined its mRNA (n= 52) and protein (n= 63) expression in paired …

Immune Profiling of Secreted Factors from Human Vestibular Schwannoma Cells and Tumor‐associated Macrophages

KM Stankovic, S Batts, DB Welling… - The …, 2024 - Wiley Online Library
Objectives This study compared the immune‐related secretory capacity of human vestibular
schwannoma (VS) and tumor‐assisted macrophages (TAMs) with their normal counterparts …

[PDF][PDF] Mechanism anti-tumor of IgA-based delivery system on the human colostral mononuclear cells via Fcα receptor

AC Honorio-França, RTS Fernandes… - … Res. Appl. Chem, 2021 - biointerfaceresearch.com
This study investigated the effect of anti-tumor of the IgA-based delivery system on the
human colostral mononuclear cells via the Fcα receptor co-cultured with breast cancer cell …

Computational studies reveal co-occurrence of two mutations in IL7R gene of high-grade serous carcinoma patients

RM Wadapurkar, A Sivaram, R Vyas - Journal of Biomolecular …, 2022 - Taylor & Francis
Major cause of mortality in ovarian cancer can be attributed to a lack of specific and sensitive
biomarkers for diagnosis and prognosis of the disease. Uncovering the mutations in genes …

Development of integrated platform of lymphocyte phenotyping, and immunotherapy validation in single cell and 3D droplet microfluidic systems

MR Sullivan - 2023 - search.proquest.com
Immunotherapies present a promising and rapidly growing field of treatment options for
cancer and other diseases. Most treatments developed by academic and industrial labs …