Porphyromonas gingivalis regulates atherosclerosis through an immune pathway

Q Ruan, P Guan, W Qi, J Li, M Xi, L Xiao… - Frontiers in …, 2023 - frontiersin.org
Atherosclerosis (AS) is a chronic inflammatory disease, involving a pathological process of
endothelial dysfunction, lipid deposition, plaque rupture, and arterial occlusion, and is one of …

Neuroinflammation: A distal consequence of periodontitis

X Li, M Kiprowska, T Kansara… - Journal of dental …, 2022 - journals.sagepub.com
Periodontitis, a chronic, inflammatory disease, induces systemic inflammation and
contributes to the development of neurodegenerative diseases. The precise etiology of the …

Unexpected relationships: Periodontal diseases: atherosclerosis–plaque destabilization? From the teeth to a coronary event

MR Czerniuk, S Surma, M Romańczyk, JM Nowak… - Biology, 2022 - mdpi.com
Simple Summary Periodontal disease and atherosclerotic cardiovascular disease are very
common around the world. Coronary artery disease is the leading cause of death. The main …

The impact of periodontitis on vascular endothelial dysfunction

Q Li, X Ouyang, J Lin - Frontiers in cellular and infection microbiology, 2022 - frontiersin.org
Periodontitis, an oral inflammatory disease, originates from periodontal microbiota dysbiosis
which is associated with the dysregulation of host immunoinflammatory response. This …

Oral microbiome mediated inflammation, a potential inductor of vascular diseases: a comprehensive review

DF Gualtero, GI Lafaurie, DM Buitrago… - Frontiers in …, 2023 - frontiersin.org
The dysbiosis of the oral microbiome and vascular translocation of the periodontopathic
microorganism to peripheral blood can cause local and systemic extra-oral inflammation …

Neuroinflammation related to the blood–brain barrier and sphingosine‐1‐phosphate in a pre‐clinical model of periodontal diseases and depression in rats

D Martín‐Hernández, M Martínez… - Journal of Clinical …, 2023 - Wiley Online Library
Aim To explore the potential mechanisms of neuroinflammation (microglia, blood–brain
barrier [BBB] permeability, and the sphingosine‐1‐phosphate [S1P] pathways) resulting …

Endothelial extracellular vesicles induce acute lung injury via follistatin-like protein 1

HX Yuan, YT Chen, YQ Li, YS Wang, ZJ Ou, Y Li… - Science China Life …, 2024 - Springer
Cardiopulmonary bypass has been speculated to elicit systemic inflammation to initiate
acute lung injury (ALI), including acute respiratory distress syndrome (ARDS), in patients …

The Link between Stroke Risk and Orodental Status—A Comprehensive Review

S Shahi, M Farhoudi, SM Dizaj, S Sharifi… - Journal of clinical …, 2022 - mdpi.com
One of the primary causes of disability and mortality in the adult population worldwide is
stroke. A person's general health is significantly impacted by their oral and dental health …

Characterizing the microbiota of cleft lip and palate patients: a comprehensive review

E Gershater, Y Liu, B Xue, MK Shin, H Koo… - Frontiers in cellular …, 2023 - frontiersin.org
Orofacial cleft disorders, including cleft lip and/or palate (CL/P), are one of the most
frequently-occurring congenital disorders worldwide. The health issues of patients with CL/P …

Porphyromonas gingivalis lipopolysaccharide induces interleukin‐6 and c‐c motif chemokine ligand 2 expression in cultured hCMEC/D3 human brain microvascular …

N Sato, T Matsumoto, S Kawaguchi, K Seya… - …, 2022 - Wiley Online Library
Objective This paper describes the effect of Porphyromonas gingivalis (P gingivalis)
lipopolysaccharide (LPS) on the expression of interleukin‐6 (IL‐6) and C‐C motif chemokine …