Importance Opioids are frequently prescribed to children and adolescents after surgery.
Prescription opioid misuse is associated with high-risk behavior in youth. Evidence-based …

This article discusses recent evidence from the peer-reviewed literature regarding the role of
local anesthetics, NSAIDs, gabapentinoids, and acetaminophen, as well as alpha-2 …

The main remit of the European Society for Paediatric Anaesthesiology (ESPA) Pain
Committee is to improve the quality of pain management in children. The ESPA Pain …

To improve postoperative pain management, several concepts have been developed,
including preemptive analgesia, preventive analgesia, and multimodal analgesia. This …

Chronic pain is the leading cause of disability in the United States. The transition from acute
to persistent pain is thought to arise from maladaptive neuroplastic mechanisms involving …

Summary Background and Objectives Perioperative pain in children can be effectively
managed with systemic opioids, but addition of paracetamol or nonsteroidal anti …

New research, regulatory guidelines, and practice initiatives have improved pain
management in infants, children, and adolescents, but obstacles remain. The aim of this …

Background: Acute pain management in children is often inadequate. The prevalence of
pain in hospitalized children in the US is unknown. Methods: We reviewed clinical …

Critically ill pediatric patients often require complex medical procedures as well as invasive
testing and monitoring which tend to be painful and anxiety-provoking, necessitating the …

Pain management in the neonatal ICU remains challenging for many clinicians and in many
complex care circumstances. The authors review general pain management principles and …