Tendinopathy describes a complex multifaceted pathology of the tendon, characterized by
pain, decline in function and reduced exercise tolerance. The most common overuse …

Tendon injuries are common and debilitating, with non-regenerative healing often resulting
in chronic disease. While there has been considerable progress in identifying the cellular …

Adult tendon tissue demonstrates a limited regenerative capacity, and the natural repair
process leaves fibrotic scar tissue with inferior mechanical properties. Surgical treatment is …

Hyperlipidemia impacts millions of people globally and has been the major risk factor for
developing atherosclerosis and cardiovascular disease. Interestingly, hyperlipidemic …

Inflammation plays an important role in the development and resolution of tendon diseases,
but underlying mechanisms are poorly understood. We therefore aimed to analyze the …

Musculoskeletal diseases involving tissue injury comprise tendon, ligament, and muscle
injury. Recently, macrophages have been identified as key players in the tendon repair …

Background Rotator cuff disease is a widespread musculoskeletal pathology and a major
cause of shoulder pain. Studies on familial predisposition suggest that genetic plays a role …

Introduction: PRPs can be used in the management of tendinopathy if we improve our
understanding of pathophysiology and to integrate molecular knowledge about PRP …

Cord blood (CB) mononuclear cell populations have demonstrated significant promise in
biomaterials-based regenerative therapies; however, the contributions of monocyte and …

Diabetes mellitus (DM) is associated with higher risk of tendinopathy, which reduces
tolerance to exercise and functional activities and affects lifestyle and glycemic control …