Design properties of hydrogel tissue-engineering scaffolds

J Zhu, RE Marchant - Expert review of medical devices, 2011 - Taylor & Francis
This article summarizes the recent progress in the design and synthesis of hydrogels as
tissue-engineering scaffolds. Hydrogels are attractive scaffolding materials owing to their …

Designing degradable hydrogels for orthogonal control of cell microenvironments

PM Kharkar, KL Kiick, AM Kloxin - Chemical Society Reviews, 2013 - pubs.rsc.org
Degradable and cell-compatible hydrogels can be designed to mimic the physical and
biochemical characteristics of native extracellular matrices and provide tunability of …

Bioactive modification of poly (ethylene glycol) hydrogels for tissue engineering

J Zhu - Biomaterials, 2010 - Elsevier
In this review, we explore different approaches for introducing bioactivity into poly (ethylene
glycol)(PEG) hydrogels. Hydrogels are excellent scaffolding materials for repairing and …

Recent advances on biomedical applications of scaffolds in wound healing and dermal tissue engineering

A Rahmani Del Bakhshayesh, N Annabi… - Artificial cells …, 2018 - Taylor & Francis
The tissue engineering field has developed in response to the shortcomings related to the
replacement of the tissues lost to disease or trauma: donor tissue rejection, chronic …

Cell encapsulation in biodegradable hydrogels for tissue engineering applications

GD Nicodemus, SJ Bryant - Tissue Engineering Part B: Reviews, 2008 - liebertpub.com
Encapsulating cells in biodegradable hydrogels offers numerous attractive features for
tissue engineering, including ease of handling, a highly hydrated tissue-like environment for …

Mechanical properties of cellularly responsive hydrogels and their experimental determination

AM Kloxin, CJ Kloxin, CN Bowman… - Advanced …, 2010 - Wiley Online Library
Hydrogels are increasingly employed as multidimensional cell culture platforms often with a
necessity that they respond to or control the cellular environment. Specifically, synthetic …

Advances in bioactive hydrogels to probe and direct cell fate

CA DeForest, KS Anseth - Annual review of chemical and …, 2012 - annualreviews.org
Advanced cell culture techniques are increasingly needed to better understand basic cell
physiology, predict in vivo response, and engineer de novo functional tissue substitutes …

Synthetic ECM: bioactive synthetic hydrogels for 3D tissue engineering

AZ Unal, JL West - Bioconjugate chemistry, 2020 - ACS Publications
The specific microenvironment that cells reside in fundamentally impacts their broader
function in tissues and organs. At its core, this microenvironment is composed of precise …

Self-assembling multidomain peptide hydrogels: designed susceptibility to enzymatic cleavage allows enhanced cell migration and spreading

KM Galler, L Aulisa, KR Regan… - Journal of the …, 2010 - ACS Publications
Multidomain peptides are a class of amphiphilic self-assembling peptides with a modular
ABA block motif in which the amphiphilic B block drives self-assembly while the flanking A …

Three-dimensional micropatterning of bioactive hydrogels via two-photon laser scanning photolithography for guided 3D cell migration

SH Lee, JJ Moon, JL West - Biomaterials, 2008 - Elsevier
Micropatterning techniques that control three-dimensional (3D) arrangement of
biomolecules and cells at the microscale will allow development of clinically relevant tissues …