Bacteria produce an array of diverse, dynamic and often complex lipid structures, some of
which function beyond their typical role in membrane structure. The model organism, E. coli …

Akkermansia muciniphila is a gut bacterium that colonizes the gut mucosa, has a role in
maintaining gut health and shows promise for potential therapeutic applications. The …

Akkermansia muciniphila, a mucophilic member of the gut microbiota, protects its host
against metabolic disorders. Because it is genetically intractable, the mechanisms …

Gene-environment interactions shape behavior and susceptibility to depression. However,
little is known about the signaling pathways integrating genetic and environmental inputs to …

It has been reported that Akkermansia muciniphila improves host metabolism and reduces
inflammation; however, its potential effects on bile acid metabolism and metabolic patterns …

The cell-envelope of Gram-negative bacteria contains endotoxic lipopolysaccharides (LPS)
that are recognized by the innate immune system via Toll-Like Receptors (TLRs). The …

Metabolic diseases are caused by a complex interplay between genetics and the
environment, yet many basic studies guiding our understanding of metabolism are confined …

The erosion of the colonic mucus layer by a dietary fiber-deprived gut microbiota results in
heightened susceptibility to an attaching and effacing pathogen, Citrobacter rodentium …

The gut microbiota is increasingly recognised as a key player in influencing human health
and changes in the gut microbiota have been strongly linked with many non-communicable …

Akkermansia muciniphila is a promising next-generation beneficial microbe due to its
natural presence in the mucus layer of the gut, its symbiotic ability to degrade mucus, and its …