[HTML][HTML] Haemostasis in cirrhosis: understanding destabilising factors during acute decompensation

A Zanetto, P Northup, L Roberts, M Senzolo - Journal of Hepatology, 2023 - Elsevier
Hospitalised patients with decompensated cirrhosis are in a rebalanced haemostatic state
due to a parallel decline in both pro-and anti-haemostatic pathways. However, this …

Overview of complications in cirrhosis

M Premkumar, AC Anand - Journal of Clinical and Experimental …, 2022 - Elsevier
Background Cirrhosis is the outcome of chronic liver disease of any etiology due to
progressive liver injury and fibrosis. Consequently, cirrhosis leads to portal hypertension …

[HTML][HTML] Acute-on-chronic liver failure: Terminology, mechanisms and management

VK Br, SK Sarin - Clinical and Molecular Hepatology, 2023 - ncbi.nlm.nih.gov
Acute-on-chronic liver failure is an acute deterioration of liver function manifesting as
jaundice and coagulopathy with the development of ascites, with a high probability of …

[HTML][HTML] Cytokine storm of COVID-19 and its impact on patients with and without chronic liver disease

M Premkumar, CK Kedarisetty - Journal of Clinical and …, 2021 - ncbi.nlm.nih.gov
The coronavirus pandemic has resulted in increased rates of hepatic decompensation,
morbidity and mortality in patients suffering from existing liver disease, and deranged liver …

Impact of SARS CoV-2/COVID-19 infection on the course of advanced chronic liver disease and hepatocellular carcinoma

M Pazgan-Simon, M Kucharska… - Pharmacological …, 2022 - Springer
Background About 20% of patients infected with SARS-CoV-2 develop COVID-19—the
disease that has dominated health care in the last two years. The course of COVID-19 in …

Features of blood clotting on thromboelastography in hospitalized patients with cirrhosis

H Shamseddeen, KR Patidar, M Ghabril… - The American journal of …, 2020 - Elsevier
Introduction Thromboelastography (TEG) provides a global assessment of hemostasis and
may have value for patients with cirrhosis who have multiple hemostatic defects. We sought …

Viscoelastic test-based bleeding risk score reliably predicts coagulopathic bleeding in decompensated cirrhosis and ACLF patients

C Bihari, A Patil, SM Shasthry, S Baweja… - Hepatology …, 2020 - Springer
Background and aims Coagulopathic bleeding risk prediction is challenging in
decompensated cirrhosis (DC) by conventional assays. Viscoelastic tests (VETs) are likely to …

COVID-19-related dynamic coagulation disturbances and anticoagulation strategies using conventional D-dimer and point-of-care Sonoclot tests: a prospective cohort …

M Premkumar, S Loganathan, K Kajal, A Hazarika… - BMJ open, 2022 - bmjopen.bmj.com
Objectives Coagulation changes associated with COVID-19 suggest the presence of a
hypercoagulable state with pulmonary microthrombosis and thromboembolic complications …

Sonoclot signature analysis: a new point-of-care testing method for defining heat stroke-induced coagulopathy

J Min, P Wan, G Liu, M Yu, L Su - International Journal of General …, 2021 - Taylor & Francis
Purpose Data regarding the incidence of a coagulable state following heat stroke as
assessed by Sonoclot signature analysis are limited. Our purpose was to appraise …

Revisiting septic shock in cirrhosis: a call for personalized management

V Girish, R Maiwall - Expert Review of Gastroenterology & …, 2024 - Taylor & Francis
Introduction Patients with cirrhosis are known to be prone to infections. Infections can trigger
organ failures and decompensations in cirrhosis. Septic shock can increase mortality by …