Biomaterial-based antimicrobial therapies for the treatment of bacterial infections

PP Kalelkar, M Riddick, AJ García - Nature Reviews Materials, 2022 - nature.com
The rise in antibiotic-resistant bacteria, including strains that are resistant to last-resort
antibiotics, and the limited ability of antibiotics to eradicate biofilms have necessitated the …

[HTML][HTML] Formulation, stabilisation and encapsulation of bacteriophage for phage therapy

DJ Malik, IJ Sokolov, GK Vinner, F Mancuso… - Advances in colloid and …, 2017 - Elsevier
Against a backdrop of global antibiotic resistance and increasing awareness of the
importance of the human microbiota, there has been resurgent interest in the potential use of …

[HTML][HTML] Biotechnological applications of bacteriophages: State of the art

LK Harada, EC Silva, WF Campos, FS Del Fiol… - Microbiological …, 2018 - Elsevier
Bacteriophage particles are the most abundant biological entities on our planet, infecting
specific bacterial hosts in every known environment and being major drivers of bacterial …

Encapsulation and delivery of therapeutic phages

B Loh, VS Gondil, P Manohar, FM Khan… - Applied and …, 2021 - Am Soc Microbiol
Delivery of therapeutic compounds to the site of action is crucial. While many chemical
substances such as beta-lactam antibiotics can reach therapeutic levels in most parts …

Recent advances in bacteriophage based biosensors for food-borne pathogen detection

A Singh, S Poshtiban, S Evoy - Sensors, 2013 - mdpi.com
Foodborne diseases are a major health concern that can have severe impact on society and
can add tremendous financial burden to our health care systems. Rapid early detection of …

Phage therapy for respiratory infections

RYK Chang, M Wallin, Y Lin, SSY Leung… - Advanced drug delivery …, 2018 - Elsevier
A respiratory infection caused by antibiotic-resistant bacteria can be life-threatening. In
recent years, there has been tremendous effort put towards therapeutic application of …

Inhaled formulations and pulmonary drug delivery systems for respiratory infections

QT Zhou, SSY Leung, P Tang, T Parumasivam… - Advanced drug delivery …, 2015 - Elsevier
Respiratory infections represent a major global health problem. They are often treated by
parenteral administrations of antimicrobials. Unfortunately, systemic therapies of high-dose …

[HTML][HTML] Bacteriophage interactions with mammalian tissue: Therapeutic applications

H Huh, S Wong, JS Jean, R Slavcev - Advanced drug delivery reviews, 2019 - Elsevier
The human body is a large reservoir for bacterial viruses known as bacteriophages
(phages), which participate in dynamic interactions with their bacterial and human hosts that …

Bacterial biosensing: Recent advances in phage-based bioassays and biosensors

U Farooq, Q Yang, MW Ullah, S Wang - Biosensors and Bioelectronics, 2018 - Elsevier
In nature, different types of bacteria including pathogenic and beneficial ones exist in
different habitats including environment, plants, animals, and humans. Among these, the …

Overcoming the challenges of phage therapy for industrial aquaculture: A review

A Culot, N Grosset, M Gautier - Aquaculture, 2019 - Elsevier
Aquaculture is the fastest-growing sector in food industry. Its development is powered by the
intensification of the production which increased bacterial disease occurrence and …