The double life of group B Streptococcus: asymptomatic colonizer and potent pathogen

B Armistead, E Oler, KA Waldorf, L Rajagopal - Journal of molecular biology, 2019 - Elsevier
Group B streptococcus (GBS) is a β-hemolytic gram-positive bacterium that colonizes the
lower genital tract of approximately 18% of women globally as an asymptomatic member of …

Group B streptococcus: virulence factors and pathogenic mechanism

Y Liu, J Liu - Microorganisms, 2022 - mdpi.com
Group B Streptococcus (GBS) or Streptococcus agalactiae is a major cause of neonatal
mortality. When colonizing the lower genital tract of pregnant women, GBS may cause …

[HTML][HTML] Evidence that intra-amniotic infections are often the result of an ascending invasion–a molecular microbiological study

R Romero, N Gomez-Lopez, AD Winters… - Journal of perinatal …, 2019 - degruyter.com
Background Microbial invasion of the amniotic cavity resulting in intra-amniotic infection is
associated with obstetrical complications such as preterm labor with intact or ruptured …

Streptococcus agalactiae induces placental macrophages to release extracellular traps loaded with tissue remodeling enzymes via an oxidative burst-dependent …

RS Doster, JA Sutton, LM Rogers, DM Aronoff… - MBio, 2018 - Am Soc Microbiol
Streptococcus agalactiae, or group B Streptococcus (GBS), is a common perinatal pathogen.
GBS colonization of the vaginal mucosa during pregnancy is a risk factor for invasive …

Hyaluronidase Impairs Neutrophil Function and Promotes Group B Streptococcus Invasion and Preterm Labor in Nonhuman Primates

M Coleman, B Armistead, A Orvis, P Quach, A Brokaw… - MBio, 2021 - Am Soc Microbiol
Invasive bacterial infections during pregnancy are a major risk factor for preterm birth,
stillbirth, and fetal injury. Group B streptococci (GBS) are Gram-positive bacteria that …

Non-human primate models to investigate mechanisms of infection-associated fetal and pediatric injury, teratogenesis and stillbirth

M Li, A Brokaw, AM Furuta, B Coler… - Frontiers in …, 2021 - frontiersin.org
A wide array of pathogens has the potential to injure the fetus and induce teratogenesis, the
process by which mutations in fetal somatic cells lead to congenital malformations. Rubella …

Group B streptococcal infections in pregnancy and early life

G Manuel, J Twentyman, K Noble… - Clinical Microbiology …, 2024 - journals.asm.org
Bacterial infections with Group B Streptococcus (GBS) are an important cause of adverse
outcomes in pregnant individuals, neonates, and infants. GBS is a common commensal in …

GBS hyaluronidase mediates immune suppression in a TLR2/4-and IL-10-dependent manner during pregnancy-associated infection

M Coleman, A Orvis, A Brokaw, A Furuta, K Sharma… - Mbio, 2023 - Am Soc Microbiol
Bacterial infections remain a significant cause of adverse pregnancy outcomes. Ascending
infection of group B streptococcus (GBS) or Streptococcus agalactiae from the lower genital …

Streptococcus agalactiae Strains with Chromosomal Deletions Evade Detection with Molecular Methods

IA Tickler, FC Tenover, S Dewell, VM Le… - Journal of clinical …, 2019 - Am Soc Microbiol
Surveillance of circulating microbial populations is critical for monitoring the performance of
a molecular diagnostic test. In this study, we characterized 31 isolates of Streptococcus …

Streptococcus agalactiae (Group B Streptococcus)

L Wu, AN Dammann, AJ Ratner - Molecular Medical Microbiology, 2024 - Elsevier
Streptococcus agalactiae (group B Streptococcus, GBS) is an important perinatal pathogen
and an emerging etiology of disease in nonpregnant adults. Despite decades of control …