In vitro and in vivo antitumor effects of the Egyptian scorpion Androctonus amoreuxi venom in an Ehrlich ascites tumor model

ML Salem, NM Shoukry, WK Teleb, MM Abdel-Daim… - Springerplus, 2016 - Springer
Scorpion venom is a highly complex mixture of about 100–700 different components, where
peptides are the major constituents with various biological and pharmacological properties …

Apoptosis induction in human leukemic cells by a novel protein Bengalin, isolated from Indian black scorpion venom: through mitochondrial pathway and inhibition of …

SD Gupta, A Gomes, A Debnath, A Saha… - Chemico-biological …, 2010 - Elsevier
Scorpion venom possesses protein toxins having numerous biological activities, some of
which are potentially anticancerous. Previously we had reported antiproliferative activity of …

[HTML][HTML] Anticancer activity a of caspian cobra (Naja naja oxiana) snake venom in human cancer cell lines via induction of apoptosis

K Ebrahim, H Vatanpour, A Zare… - Iranian journal of …, 2016 - ncbi.nlm.nih.gov
Cancer is the leading cause of death worldwide. Current anticancer drugs involve various
toxic side effects; efforts are ongoing to develop new anticancer agents especially from the …

Scorpion venom (Odontobuthus doriae) induces apoptosis by depolarization of mitochondria and reduces S-phase population in human breast cancer cells (MCF-7)

J Zargan, S Umar, M Sajad, M Naime, S Ali, HA Khan - Toxicology in vitro, 2011 - Elsevier
Venom of some species of scorpions induces apoptosis and arrests proliferation in cancer
cells. This is an important property that can be harnessed and can lead to isolation of …

Scorpion (Odontobuthus doriae) venom induces apoptosis and inhibits DNA synthesis in human neuroblastoma cells

J Zargan, M Sajad, S Umar, M Naime, S Ali… - Molecular and cellular …, 2011 - Springer
Scorpion and its organs have been used to cure epilepsy, rheumatism, and male impotency
since medieval times. Scorpion venom which contains different compounds like enzyme and …

Snake venom toxins as potential therapeutic agents in the treatment of prostate cancer

J Ochoa-Mosquera, A Montoya-Gómez… - Molecular Biology …, 2024 - Springer
Prostate cancer is a significant global health concern and one of the leading causes of death
from diseases in men. There is a growing interest in exploring new therapeutic approaches …

In vitro analysis of the anticancer properties of scorpion venom in colorectal and breast cancer cell lines

AK Al‑Asmari, M Islam… - Oncology letters, 2016 - spandidos-publications.com
Scorpion venom contains various types of proteins and peptides that are able to act as
inhibitors of neurotransmitter molecules. This is achieved primarily via the inhibition of ion …

Snake Venoms-Based Compounds as Potential Anticancer Prodrug: Sand Viper Cerastes Cerastes as a Model

M Aziz, MA Abdel-Rahman, O Abbas… - Egyptian Journal of …, 2022 - ejchem.journals.ekb.eg
Cancer is a major public health problem, recently known as the disease of the millennium.
Proliferation of tumor cells, angiogenesis and the relationship between cancer cells and …

Cytotoxic effect of Leurius quinquestratus (scorpion) venom in different human cancer cell lines in vitro

WM Salama, SA El-Naggar - Tropical Journal of Pharmaceutical Research, 2021 - ajol.info
Purpose: In this study, the cytotoxicity of scorpion Leurius quinquestratus crude venom
(LQCV) was evaluated in vitro in selected human cancer cell lines. Methods: Breast (MCF …

Scorpion venom component III inhibits cell proliferation by modulating NF-κB activation in human leukemia cells

X Song, G Zhang, A Sun, J Guo… - Experimental and …, 2012 - spandidos-publications.com
Scorpion venom contains various groups of compounds that exhibit anticancer activity
against a variety of malignancies through a poorly understood mechanism. While the …