Spinal cord injury (SCI) is a traumatic event from which there is limited recovery of function,
despite the best efforts of many investigators to devise realistic therapeutic treatments. Partly …

Rehabilitative training is currently one of the most successful treatments to promote
functional recovery following spinal cord injury. Nevertheless, there are many unanswered …

During bipedal locomotor activities, humans use elements of quadrupedal neuronal limb
control. Evolutionary constraints can help inform the historical ancestry for preservation of …

Mitochondrial dysfunction is becoming a pivotal target for neuroprotective strategies
following contusion spinal cord injury (SCI) and the pharmacological compounds that …

In the early 1980s experiments on spinalized cats showed that exercise training on the
treadmill could enhance locomotor recovery after spinal cord injury (SCI). In this review, we …

Performance of a motor task is improved by practicing a specific task with added 'challenges'
to a training regimen. We tested the hypothesis that, in the absence of brain control, the …

Rehabilitative motor training is currently one of the most widely used approaches to promote
moderate recovery following injuries of the central nervous system. Such training is …

Task specific rehabilitation training is commonly used to treat motor dysfunction after
neurological injures such as spinal cord injury (SCI), yet the use of task specific training in …

The endoplasmic reticulum (ER) stress response (ERSR) is activated to maintain protein
homeostasis or induce apoptosis in the ER in response to distinct cellular insults including …

This review is based on a lecture presented at the Craig H. Neilsen Foundation sponsored
Spinal Cord Injury Training Program at Ohio State University. We discuss the advantages …