Healthy outcomes of patients with COVID-19 two years after the infection: a prospective cohort study

D Li, X Liao, Z Liu, Z Ma, J Dong, G Zheng… - Emerging Microbes & …, 2022 - Taylor & Francis
The long-term effect of coronavirus disease 2019 (COVID-19) has been rarely known. This
study aimed to investigate healthy outcomes of COVID-19 survivors up to 2 years after the …

Pharmacokinetic considerations to optimize clinical outcomes for COVID-19 drugs

CK Nwabufo, R Bendayan - Trends in Pharmacological Sciences, 2022 - cell.com
The development of clinically effective drugs that could complement existing vaccines is
urgently needed to reduce the morbidity and mortality associated with COVID-19. Drug …

[HTML][HTML] SARS-CoV-2 effects on the male genitourinary system

ZM Connelly, D Whitaker, A Dullea… - American journal of …, 2022 - ncbi.nlm.nih.gov
SARS-CoV-2 infection arose in 2019 and has changed life as we know it. With our ever-
advancing knowledge, therapies, and vaccines, more functions of the SARS-CoV-2 virus are …

In vitro evidence against productive SARS-CoV-2 infection of human testicular cells: Bystander effects of infection mediate testicular injury

S Giannakopoulos, DP Strange, B Jiyarom… - PLoS …, 2023 - journals.plos.org
The hallmark of severe COVID-19 involves systemic cytokine storm and multi-organ injury
including testicular inflammation, reduced testosterone, and germ cell depletion. The ACE2 …

Divergent androgenic modulation of SARS-CoV-2 infection cooperates with dysregulated immune response to dictate worse COVID-19 outcomes in men

M Duarte-Silva, CNS Oliveira, C Fuzo… - Brain, behavior, and …, 2023 - Elsevier
Background Sex-determined differences are rarely addressed in the management of
diseases, despite well-known contrasting outcomes between female and male patients. In …

[HTML][HTML] Peroxide derivatives as SARS-CoV-2 entry inhibitors

D Zhang, Q Ma, M Yang, YY Belyakova, Z Yang… - Virus Research, 2024 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the ongoing
coronavirus disease 2019 (COVID-19) pandemic. Host cell invasion is mediated by the …

Viral tropism for the testis and sexual transmission

F Wang, J Zhang, Y Wang, Y Chen, D Han - Frontiers in Immunology, 2022 - frontiersin.org
The mammalian testis adopts an immune privileged environment to protect male germ cells
from adverse autoimmune reaction. The testicular immune privileged status can be also …

Pro: does COVID affect male reproductive health?

R Golan, A Muthigi, R Ramasamy - Journal of Urology, 2022 - journals.lww.com
SARS-CoV-2 is a respiratory virus, yet it can present with extrapulmonary manifestations
and may impact body systems well beyond the initial infection. SARS-CoV-2 uses human …

Developing Experimental and Computational Approaches to Characterize Viral Distribution, Spread, and Variant Emergence

E Normandin - 2022 - search.proquest.com
Many viral mutations that impact human pathogenicity arise over the course of disease, yet
intrahost viral dynamics remain poorly characterized. Mutations that emerge during infection …

Representações sociais e profissionais da saúde: saúde sexual e reprodutiva dos homens, masculinidades e infertilidade

AF Souza - 2022 - repositorio.ufsm.br
Falar sobre saúde sexual e reprodutiva é um desafio, visto que a temática ainda é
carregada de mitos e preconceitos. O tema necessita que se tenha um olhar amplo …