Radiation therapy has been used worldwide for many decades as a therapeutic regimen for
the treatment of different types of cancer. Just over 50% of cancer patients are treated with …

Background and purpose The effects of radiation on the heart are dependent on dose,
fractionation, overall treatment time, and pre-existing cardiovascular pathology. Murine …

Circadian disruption has been linked to cancer development, progression, and radiation
response. Clinical evidence to date shows that circadian genetic variation and time of …

Redox and metabolic processes are tightly coupled in both physiological and pathological
conditions. In cancer, their integration occurs at multiple levels and is characterized by …

Cell senescence is a crucial process in cell fate determination and is involved in an
extensive array of aging-associated diseases. General perceptions and experimental …

During evolution, humans are acclimatized to the stresses of natural radiation and circadian
rhythmicity. Radiosensitivity of mammalian cells varies in the circadian period and adaptive …

Five decades ago, Franz Halberg conceived the idea of​​ a circadian-based therapy for
cancer, given the differential tolerance to treatment derived from the intrinsic host rhythms …

Acquired radio-resistance is thought to be one of the main causes of recurrent metastasis
after failure of nasopharyngeal carcinoma (NPC) radiotherapy, which may be related to X …

Radiation-induced dermatitis is a common occurrence in cancer patients undergoing
radiation therapy (RT) and is caused when ionizing radiation (IR) induces DNA strand …

Skin cancer is the most diagnosed type of cancer in the United States, and while most of
these malignancies are highly treatable, treatment costs still exceed $8 billion annually …