Chronic graft-versus-host disease (GVHD) is a major cause of morbidity and mortality in long-
term survivors of allogeneic stem cell transplantation. The immunopathogenesis of chronic …

Sjögren's syndrome (SS) is a chronic autoimmune disorder that is characterized by
dysfunction and destruction of the exocrine glands. Exocrinopathy is associated with …

B cell-activating factor (BAFF) has a key role in promoting B-lymphocyte activation and
survival in primary Sjögren's syndrome (pSS). The cellular origin of BAFF overexpression in …

Objective Exosomes are membrane vesicles of endosomal origin that are distinct from
apoptotic bodies and are thought to represent an acellular mechanism for antigen transfer to …

Sjogren's syndrome (SS) is a chronic autoimmune disease characterized by the infiltration of
exocrine glands including salivary and lachrymal glands responsible for the classical dry …

The CD40–CD40L costimulatory pathway is involved in the evolution of many autoimmune
diseases including systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and …

Objective A major characteristic of the autoimmune disease primary Sjögren's syndrome
(SS) is salivary gland (SG) hypofunction. The inability of resident SG stem cells (SGSC s) to …

Context: Serum levels of the sex steroid prohormones dehydroepiandrosterone (DHEA) and
DHEA sulfate (DHEA-S) decline upon aging and are reduced in primary Sjogren's …

CD40 has been identified in an expanding list of haematopoietic and non-haematopoietic
cells and has received an increased interest based on its role in a variety of cell-mediated …

Objective. Adiponectin is an adipocytokine that displays insulin-sensitizing and
immunoregulatory properties. Adipocyte development in association with fibrosis is …