Patient-reported barriers to adherence to antiretroviral therapy: a systematic review and meta-analysis

Z Shubber, EJ Mills, JB Nachega, R Vreeman… - PLoS …, 2016 - journals.plos.org
Background Maintaining high levels of adherence to antiretroviral therapy (ART) is a
challenge across settings and populations. Understanding the relative importance of …

Depression and adherence to antiretroviral therapy in low-, middle-and high-income countries: a systematic review and meta-analysis

OA Uthman, JF Magidson, SA Safren… - Current Hiv/aids …, 2014 - Springer
We investigated the associations between depressive symptoms and adherence to
antiretroviral therapy (ART) among people living with HIV (PLHIV). We searched the …

Initiation of long-acting cabotegravir plus rilpivirine as direct-to-injection or with an oral lead-in in adults with HIV-1 infection: week 124 results of the open-label phase …

C Orkin, EB Morell, DHS Tan, H Katner… - The Lancet …, 2021 - thelancet.com
Background Previous work established non-inferiority of switching participants who were
virologically suppressed from daily oral standard of care to monthly long-acting …

Long-acting parenteral drug delivery systems for the treatment of chronic diseases

AB Jindal, AR Bhide, S Salave, D Rana… - Advanced Drug Delivery …, 2023 - Elsevier
The management of chronic conditions often requires patients to take daily medication for an
extended duration. However, the need for daily dosing can lead to nonadherence to the …

Doravirine/lamivudine/tenofovir disoproxil fumarate is non-inferior to efavirenz/emtricitabine/tenofovir disoproxil fumarate in treatment-naive adults with human …

C Orkin, KE Squires, JM Molina, PE Sax… - Clinical Infectious …, 2019 - academic.oup.com
Background Doravirine (DOR), a novel non-nucleoside reverse-transcriptase inhibitor
(NNRTI), is active against wild-type Human Immunodeficiency Virus (HIV)-1 and the most …

Interventions to improve adherence to antiretroviral therapy: a rapid systematic review

KH Chaiyachati, O Ogbuoji, M Price, AB Suthar… - Aids, 2014 - journals.lww.com
Design: A rapid systematic review. Methods: We conducted a rapid systematic review of the
global evidence on interventions to improve adherence to ART, utilizing pre-existing …

The evolution of three decades of antiretroviral therapy: challenges, triumphs and the promise of the future

A Tseng, J Seet, EJ Phillips - British journal of clinical …, 2015 - Wiley Online Library
The evolution of human immunodeficiency virus (HIV) treatment has improved our
understanding and management of complex pharmacological issues that have driven …

[HTML][HTML] Development of an oral once-weekly drug delivery system for HIV antiretroviral therapy

AR Kirtane, O Abouzid, D Minahan, T Bensel… - Nature …, 2018 - nature.com
The efficacy of antiretroviral therapy is significantly compromised by medication non-
adherence. Long-acting enteral systems that can ease the burden of daily adherence have …

Systematic review: patient‐reported outcomes in chronic hepatitis C‐the impact of liver disease and new treatment regimens

Z Younossi, L Henry - Alimentary pharmacology & therapeutics, 2015 - Wiley Online Library
Background Treatment for chronic hepatitis C (CH‐C) is rapidly changing and moving away
from an interferon and ribavirin‐based therapy to interferon‐free ribavirin‐free all oral …

Ritonavir-boosted darunavir combined with raltegravir or tenofovir–emtricitabine in antiretroviral-naive adults infected with HIV-1: 96 week results from the NEAT001 …

F Raffi, AG Babiker, L Richert, JM Molina, EC George… - The Lancet, 2014 - thelancet.com
Background Standard first-line antiretroviral therapy for HIV-1 infection includes two
nucleoside or nucleotide reverse transcriptase inhibitors (NtRTIs), but these drugs have …