An automated multi-modal graph-based pipeline for mouse genetic discovery

Z Fang, G Peltz - Bioinformatics, 2022 - academic.oup.com
Motivation Our ability to identify causative genetic factors for mouse genetic models of
human diseases and biomedical traits has been limited by the difficulties associated with …

[HTML][HTML] Genetic Discovery Enabled by A Large Language Model

T Tu, Z Fang, Z Cheng, S Spasic, A Palepu… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Artificial intelligence (AI) has been used in many areas of medicine, and recently large
language models (LLMs) have shown potential utility for clinical applications. However …

Compendious survey of protein tandem repeats in inbred mouse strains

A Arslan - BMC Genomic Data, 2022 - Springer
Short tandem repeats (STRs) play a crucial role in genetic diseases. However, classic
disease models such as inbred mice lack such genome wide data in public domain. The …

[HTML][HTML] Systematic inspection of genomic tandem repeats and rearrangements in autism model

A Arslan - Brain Disorders, 2022 - Elsevier
The mouse model for autism, BTBRT+ Itpr3 tf/J (BTBR), has been intensively studied for
various biological anomalies at genomic, transcriptomics and proteomics levels. However …

[PDF][PDF] Experimental precision medicine: Mouse models to test precision medicine

DG Ashbrook - 2023 - opar.io
We require experimental populations in which to test precision medicine interventions
before they can be translated to humans. Mouse models can provide immortal genometypes …