Meiosis is a key event of sexual life cycles in eukaryotes. Its mechanistic details have been
uncovered in several model organisms, and most of its essential features have received …

Meiosis presents many important mysteries that await elucidation. Here we discuss two such
aspects. First, we consider how the current meiotic program might have evolved. We …

Chromosome errors, or aneuploidy, affect an exceptionally high number of human
conceptions, causing pregnancy loss and congenital disorders. Here, we have followed …

Crossover recombination reshuffles genes and prevents errors in segregation that lead to
extra or missing chromosomes (aneuploidy) in human eggs, a major cause of pregnancy …

According to Mendel's second law, chromosomes segregate randomly in meiosis. Non-
random segregation is primarily known for cases of selfish meiotic drive in females, in which …

The nematode Caenorhabditis elegans has shed light on many aspects of eukaryotic
biology, including genetics, development, cell biology, and genomics. A major factor in the …

Comparisons among a variety of eukaryotes have revealed considerable variability in the
structures and processes involved in their meiosis. Nevertheless, conventional forms of …

Centromeres are essential for chromosome segregation in eukaryotes, yet their specification
is unexpectedly diverse among species and can involve major transitions such as those …

Centromeres strongly affect (epi) genomic architecture and meiotic recombination dynamics,
influencing the overall distribution and frequency of crossovers. Here we show how …

Although the development of super-resolution microscopy methods dates back to 1994,
relevant applications in plant cell imaging only started to emerge in 2010. Since then, the …