One-carbon metabolism in neurodevelopmental disorders: using broad-based nutraceutics to treat cognitive deficits in complex spectrum disorders

L Schaevitz, J Berger-Sweeney, L Ricceri - Neuroscience & Biobehavioral …, 2014 - Elsevier
Folate and choline, two nutrients involved in the one-carbon metabolic cycle, are intimately
involved in regulating DNA integrity, synthesis, biogenic amine synthesis, and methylation …

Ameliorative role of chitosan nanoparticles against silver nanoparticle-induced reproductive toxicity in male albino rats

AAE Mahgoob, E Tousson, MA Abd Eldaim… - … Science and Pollution …, 2023 - Springer
This study was designed to evaluate the protective potentials of chitosan nanoparticles
(ChNPs) against silver nanoparticle (AgNP)-induced reproductive toxicity in male Wister …

Effects of folic acid on testicular toxicity induced by bisphenol-A in male Wistar rats

O Gules, M Yildiz, Z Naseer, M Tatar - Biotechnic & Histochemistry, 2019 - Taylor & Francis
We investigated the protective effect of the folic acid (FA) against bisphenol-A (BPA) induced
toxicity in rat testis. We used four groups of seven adult male Wistar albino rats. The control …

Costus root extract alleviates blood biochemical derangements of experimentally-induced hypo-and hyperthyroidism in mice

Y Bolkiny, E Tousson, A El-Atrsh… - Annual Research & …, 2019 - open.journal4submit.com
Objectives: Thyroid hormones regulate all metabolic activities; therefore, it is not amazing
that hepatic; renal dysfunctions and lipid alterations are commonly detected in patients with …

Comparison of the effect of a combination of eight micronutrients versus a standard mono preparation on sperm parameters

M Lipovac, F Bodner, M Imhof, P Chedraui - Reproductive Biology and …, 2016 - Springer
Background There are reports showing that l-carnitine alone or in combination with other
micronutrients improve sperm parameters. However, comparative studies are still lacking …

Effect of ethanol on the changes in testicular protein expression in adult male rats

N Tangsrisakda, S Iamsaard - Andrologia, 2020 - Wiley Online Library
Ethanol consumption is a major cause of male infertility, but the exact mechanism is still
largely unknown. This study attempted to investigate the effect of ethanol on sperm …

Ethoxyquin inhibits the progression of murine ehrlich ascites carcinoma through the inhibition of autophagy and LDH

F Tayel, ME Mahfouz, AF Salama, MA Mansour - Biomedicines, 2021 - mdpi.com
Cancer cells exhibit an increased glycolysis rate for ATP generation (the Warburg effect) to
sustain an increased proliferation rate. In tumor cells, the oxidation of pyruvate in the Krebs …

Thyroidectomy induced hepatic toxicity and possible amelioration by Ginkgo biloba leaf extract

E Tousson, AJM Alghabban, H Abou Harga - Biomedicine & Preventive …, 2014 - Elsevier
The liver is a major target organ for thyroid hormone action and marked changes occur in
liver functions in the case of hypo-or hyperthyroidism. This studied aimed at inverstigating …

Hemodynamic properties and arterial structure in male rat offspring with fetal hypothyroidism.

M Ghanbari, F Bagheripuor, A Piryaei… - General physiology …, 2016 - europepmc.org
Thyroid hormones (THs) play a crucial role in the development of different systems during
fetal life; fetal hypothyroidism (FH) is associated with reduced cardiac function and …

Histopathological and immunohistochemical alterations in rat heart after thyroidectomy and the role of hemin and ketoconazole in treatment

E Tousson, EM Ali, W Ibrahim, RM Ashraf - Biomedicine & …, 2012 - Elsevier
The heart is a major target organ for thyroid hormone action and marked changes occur in
cardiac function in the case of hypo-or hyperthyroidism. Also, thyroid hormone has a …