Harnessing the power of immune cells, especially T cells, to enhance anti-tumor activities
has become a promising strategy in clinical management of hematologic malignancies. The …

Although antibodies are well developed and widely used in cancer therapy and diagnostic
fields, some defects remain, such as poor tissue penetration, long in vivo metabolic …

Chimeric antigen receptor (CAR)-T cell therapy has shown impressive results in
chemorefractory B cell malignancies, raising the possibilities of using this …

Proteins and peptides have emerged in recent years to treat a wide range of multifaceted
diseases such as cancer, diabetes and inflammation. The emergence of polypeptides has …

Differential scanning calorimetry (DSC) has been extensively used in the biopharmaceutical
industry to characterize protein thermal stability and domain folding integrity. Recently, nano …

Simple Summary The ultimate goal of T cell-engaging immunotherapy is to endorse the
activity of a person's own cytotoxic T cells in the tumor microenvironment, finally destroying …

В настоящем обзоре обсуждается относительно новый класс направленных адресных
молекул, активно исследующийся в отношении радионуклидной диагностики и лечения …

Background Cervical cancer remains the second leading cause of mortality in women in
developing countries. While surgery, chemotherapy, radiotherapy, and vaccine therapy are …

Scaffold-based protein libraries are designed to be both diverse and rich in functional/folded
proteins. However, introducing an extended diversity while preserving stability of the initial …

The exquisite specificity of antibodies and antibody fragments renders them excellent agents
for targeted delivery of radionuclides. Radiolabeled antibodies and fragments have been …