[HTML][HTML] Modern isolation and separation techniques for extracellular vesicles

T Liangsupree, E Multia, ML Riekkola - Journal of Chromatography A, 2021 - Elsevier
Extracellular vesicles (EVs) are heterogenous membrane-bound vesicles released from
various origins. EVs play a crucial role in cellular communication and mediate several …

Using single-vesicle technologies to unravel the heterogeneity of extracellular vesicles

G Bordanaba-Florit, F Royo, SG Kruglik… - Nature …, 2021 - nature.com
Extracellular vesicles (EVs) are heterogeneous lipid containers with a complex molecular
cargo comprising several populations with unique roles in biological processes. These …

New technologies for analysis of extracellular vesicles

H Shao, H Im, CM Castro, X Breakefield… - Chemical …, 2018 - ACS Publications
Extracellular vesicles (EVs) are diverse, nanoscale membrane vesicles actively released by
cells. Similar-sized vesicles can be further classified (eg, exosomes, microvesicles) based …

Methodological guidelines to study extracellular vesicles

FAW Coumans, AR Brisson, EI Buzas… - Circulation …, 2017 - Am Heart Assoc
Owing to the relationship between extracellular vesicles (EVs) and physiological and
pathological conditions, the interest in EVs is exponentially growing. EVs hold high hopes …

Blood-based cancer biomarkers in liquid biopsy: a promising non-invasive alternative to tissue biopsy

J Marrugo-Ramírez, M Mir, J Samitier - International journal of molecular …, 2018 - mdpi.com
Cancer is one of the greatest threats facing our society, being the second leading cause of
death globally. Currents strategies for cancer diagnosis consist of the extraction of a solid …

Microfluidics for exosome isolation and analysis: enabling liquid biopsy for personalized medicine

JC Contreras-Naranjo, HJ Wu, VM Ugaz - Lab on a Chip, 2017 - pubs.rsc.org
Exosomes, the smallest sized extracellular vesicles (∽ 30–150 nm) packaged with lipids,
proteins, functional messenger RNAs and microRNAs, and double-stranded DNA from their …

Advances in microfluidics for lipid nanoparticles and extracellular vesicles and applications in drug delivery systems

M Maeki, N Kimura, Y Sato, H Harashima… - Advanced drug delivery …, 2018 - Elsevier
Lipid-based nanobiomaterials as liposomes and lipid nanoparticles (LNPs) are the most
widely used nanocarriers for drug delivery systems (DDSs). Extracellular vesicles (EVs) and …

Extracellular vesicles: techniques and biomedical applications related to single vesicle analysis

J Zhang, J Wu, G Wang, L He, Z Zheng, M Wu… - ACS …, 2023 - ACS Publications
Extracellular vesicles (EVs) are extensively dispersed lipid bilayer membrane vesicles
involved in the delivery and transportation of molecular payloads to certain cell types to …

Glycosylation of extracellular vesicles: current knowledge, tools and clinical perspectives

C Williams, F Royo, O Aizpurua-Olaizola… - Journal of …, 2018 - Taylor & Francis
It is now acknowledged that extracellular vesicles (EVs) are important effectors in a vast
number of biological processes through intercellular transfer of biomolecules. Increasing …

Microfluidics-based on-a-chip systems for isolating and analysing extracellular vesicles

SC Guo, SC Tao, H Dawn - Journal of extracellular vesicles, 2018 - Taylor & Francis
Extracellular vesicles (EVs), which can be found in almost all body fluids, consist of a lipid
bilayer enclosing proteins and nucleic acids from their cells of origin. EVs can transport their …