Non-small cell lung cancer (NSCLC), which represents 80–85% of lung cancer cases, is one
of the leading causes of human death worldwide. The majority of patients undergo an …

Lung cancer is the second most prevalent cancer and the leading cause of cancer‐related
death worldwide. Surgery, chemotherapy, molecular targeted therapy, immunotherapy, and …

Aberrant Notch signaling profoundly affects cancer progression. Especially the Notch3
receptor was found to be dysregulated in cancer, where its expression is correlated with …

The evolutionarily-conserved Notch signaling pathway plays critical roles in cell
communication, function and homeostasis equilibrium. The pathway serves as a cell-to-cell …

Simple Summary The Notch signaling pathway regulates cell proliferation, apoptosis, stem
cell self-renewal, and differentiation in a context-dependent fashion both during embryonic …

The Notch signaling pathway plays pivotal roles in cell proliferation, stemness and invasion
of non-small cell lung cancer (NSCLC). The human Notch family consists of four receptors …

One of the most important issues in cancer progression is caner stem cells (CSCs) which
have illustrated that the bulk tumors can arise from a special combination of cells …

Background: Early data showed that FOXP3 could induce epithelial-mesenchymal transition
by stimulating the Wnt/β-catenin signaling pathway in non-small cell lung cancer (NSCLC) …

Globally, lung cancer contributes significantly to the public health burden–associated
mortality. As this form of cancer is insidious in nature, there is an inevitable diagnostic delay …

Standard chemotherapy is commonly used in clinical practice for the treatment of non-small
cell lung cancer (NSCLC). However, its therapeutic efficacy remains low. Combination …