Keratin 19 binds and regulates cytoplasmic HNRNPK mRNA targets in triple-negative breast cancer

A Fallatah, DG Anastasakis, A Manzourolajdad… - BMC Molecular and Cell …, 2023 - Springer
Background Heterogeneous nuclear ribonucleoprotein K (HNRNPK) regulates pre-mRNA
processing and long non-coding RNA localization in the nucleus. It was previously shown …

High-throughput platform for yeast morphological profiling predicts the targets of bioactive compounds

S Ohnuki, I Ogawa, K Itto-Nakama, F Lu… - npj systems biology …, 2022 - nature.com
Morphological profiling is an omics-based approach for predicting intracellular targets of
chemical compounds in which the dose-dependent morphological changes induced by the …

Cell adhesion molecules affected by ionizing radiation and estrogen in an experimental breast cancer model

GM Calaf, LA Crispin, JP Muñoz, F Aguayo… - International Journal of …, 2022 - mdpi.com
Cancer develops in a multi-step process where environmental carcinogenic exposure is a
primary etiological component, and where cell–cell communication governs the biological …

Keratin 19 interacts with GSK3β to regulate its nuclear accumulation and degradation of cyclin D3

P Sharma, S Tiufekchiev, V Lising… - Molecular biology of …, 2021 - Am Soc Cell Biol
Cyclin D3 regulates the G1/S transition and is frequently overexpressed in several cancer
types including breast cancer, where it promotes tumor progression. Here we show that a …

Keratin 19 maintains E-cadherin localization at the cell surface and stabilizes cell-cell adhesion of MCF7 cells

S Alsharif, P Sharma, K Bursch, R Milliken… - Cell adhesion & …, 2021 - Taylor & Francis
ABSTRACT A cytoskeletal protein keratin 19 (K19) is highly expressed in breast cancer but
its effects on breast cancer cell mechanics are unclear. In MCF7 cells where K19 expression …

Tracking single cells motility on different substrates

P Sharma, VK Lam, CB Raub, BM Chung - Methods and protocols, 2020 - mdpi.com
Motility is a key property of a cell, required for several physiological processes, including
embryonic development, axon guidance, tissue regeneration, gastrulation, immune …

A novel flushing technique to improve micro-EDM dressing process stability: assessment through analyzing debris evacuation

MS Shah, D Gupta, P Saha, A Assam… - The International Journal of …, 2023 - Springer
This paper aims to develop an efficient debris-flushing technique for micro-EDM dressing to
improve its process stability by providing a rotation to the dielectric medium. A setup was …

Неструктурная роль цитокератинов при злокачественных новообразованиях

МА Болдышевская, ЛА Таширева… - Успехи …, 2023 - umo.abvpress.ru
Аннотация Цитокератины (ЦК) являются промежуточными филаментами цитоскелета
эпителиальных клеток и обеспечивают специфическую структуру и морфологию …

Regulation of keratins in colonocytes during inflammatory signaling

K Kähärä - 2023 - doria.fi
The colon is part of the gastrointestinal tract, with the main function of absorbing water,
moving and storing fecal material as well as inhabiting micro-organisms. Keratins are …

[图书][B] Regulation of Cell Cycle Progression by Keratin 19 in Breast Cancer Cells

P Sharma - 2021 - search.proquest.com
Keratins are widely used as diagnostic markers to detect tumors in both primary and distal
sites and to determine tumors' tissue of origin in order to aid in treatment strategies. In this …