Chronic kidney disease (CKD) is a chronic renal dysfunction syndrome that is characterized
by nephron loss, inflammation, myofibroblasts activation, and extracellular matrix (ECM) …

MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression by
degrading or repressing the translation of their target messenger RNAs. As miRNAs are …

Initiation of cyst formation in autosomal dominant polycystic kidney disease (ADPKD) occurs
when kidney tubule cells are rendered null for either PKD1 or PKD2 by somatic 'second …

Autosomal dominant polycystic kidney disease (ADPKD) is a common monogenic disorder
marked by numerous progressively enlarging kidney cysts. Mettl3, a methyltransferase that …

Autosomal dominant polycystic kidney disease (ADPKD), among the most common human
genetic conditions and a frequent etiology of kidney failure, is primarily caused by …

Lipotoxicity is the dysregulation of the lipid environment and/or intracellular composition that
leads to accumulation of harmful lipids and ultimately to organelle dysfunction, abnormal …

Aeromonas salmonicides is a type of Gram-negative bacteria and has become the main fish
pathogen in aquaculture because of its characteristics of worldwide distribution, broad host …

Abstract Interleukin (IL)− 33 is a tissue-derive proinflammatory cytokine that promotes
fibrosis in systemic sclerosis (SSc). microRNA (miR)− 214 expression has been elaborated …

Background Emerging evidence indicates that epigenetic modulation of gene expression
plays a key role in the progression of autosomal dominant polycystic kidney disease …

MicroRNAs (miRNAs) are small, non-coding RNA molecules that play a crucial role in
regulating gene expression by inhibiting the translation of their specific target messenger …