Advances in nanomaterials for photodynamic therapy applications: Status and challenges

J Chen, T Fan, Z Xie, Q Zeng, P Xue, T Zheng, Y Chen… - Biomaterials, 2020 - Elsevier
Photodynamic therapy (PDT), as a non-invasive therapeutic modality that is alternative to
radiotherapy and chemotherapy, is extensively investigated for cancer treatments. Although …

Gold nanoparticles in diagnostics and therapeutics for human cancer

P Singh, S Pandit, V Mokkapati, A Garg… - International journal of …, 2018 - mdpi.com
The application of nanotechnology for the treatment of cancer is mostly based on early tumor
detection and diagnosis by nanodevices capable of selective targeting and delivery of …

Nanoparticles in photodynamic therapy

SS Lucky, KC Soo, Y Zhang - Chemical reviews, 2015 - ACS Publications
Cancer accounted for 7.6 million deaths (around 13% of all deaths) worldwide in 2008.(1)
Almost 13 million cancer cases are newly diagnosed every year, and deaths are projected to …

Inorganic nanomaterials with intrinsic singlet oxygen generation for photodynamic therapy

MR Younis, G He, J Qu, J Lin, P Huang… - Advanced …, 2021 - Wiley Online Library
Inorganic nanomaterials with intrinsic singlet oxygen (1O2) generation capacity, are
emerged yet dynamically developing materials as nano‐photosensitizers (NPSs) for …

An O2 Self‐Sufficient Biomimetic Nanoplatform for Highly Specific and Efficient Photodynamic Therapy

H Cheng, JY Zhu, SY Li, JY Zeng, Q Lei… - Advanced Functional …, 2016 - Wiley Online Library
Conventional oxygen‐dependent photodynamic therapy (PDT) has faced severe challenges
because of the non‐specificity of most available photosensitizers (PSs) and the hypoxic …

Manipulating tumor hypoxia toward enhanced photodynamic therapy (PDT)

J Dang, H He, D Chen, L Yin - Biomaterials Science, 2017 - pubs.rsc.org
Photodynamic therapy (PDT) is considered a promising approach for the treatment of cancer
and is achieved via the photosensitizer (PS)-mediated incomplete reduction of oxygen upon …

Beyond photo: Xdynamic therapies in fighting cancer

S Wang, R Tian, X Zhang, G Cheng, P Yu… - Advanced …, 2021 - Wiley Online Library
Reactive oxygen species (ROS)‐related therapeutic approaches are developed as a
promising modality for cancer treatment because the aberrant increase of intracellular ROS …

Constructing adaptive photosensitizers via supramolecular modification based on pillararene host–guest interactions

L Shao, Y Pan, B Hua, S Xu, G Yu… - Angewandte Chemie …, 2020 - Wiley Online Library
In order to promote the development of photodynamic therapy (PDT), undesired side effects
like low tumor specificity and the “always‐on” phenomenon should be avoided. An effective …

A photosensitizer-loaded DNA origami nanosystem for photodynamic therapy

X Zhuang, X Ma, X Xue, Q Jiang, L Song, L Dai… - ACS …, 2016 - ACS Publications
Photodynamic therapy (PDT) offers an alternative for cancer treatment by using ultraviolet or
visible light in the presence of a photosensitizer and molecular oxygen, which can produce …

Antimicrobial photosensitizers: drug discovery under the spotlight

R Yin, M R. Hamblin - Current medicinal chemistry, 2015 - benthamdirect.com
Although photodynamic therapy (PDT) was discovered over a hundred years ago by its
ability to destroy microorganisms, it has been developed mainly as a cancer therapy. In …