Cardiovascular manifestations from therapeutic radiation: a multidisciplinary expert consensus statement from the International Cardio-Oncology Society

JD Mitchell, DA Cehic, M Morgia, C Bergom, J Toohey… - Cardio Oncology, 2021 - jacc.org
Radiation therapy is a cornerstone of cancer therapy, with> 50% of patients undergoing
therapeutic radiation. As a result of widespread use and improved survival, there is …

[HTML][HTML] Cancer-related stroke: an emerging subtype of ischemic stroke with unique pathomechanisms

OY Bang, JW Chung, MJ Lee, WK Seo, GM Kim… - Journal of …, 2020 - ncbi.nlm.nih.gov
Systemic cancer and ischemic stroke are common conditions and two of the most frequent
causes of death among the elderly. The association between cancer and stroke has been …

Amygdalar activity measured using FDG-PET/CT at head and neck cancer staging independently predicts survival

MZO Hassan, A Tawakol, Y Wang, RM Alvi… - PloS one, 2023 - journals.plos.org
Importance The mechanisms underlying the association between chronic stress and higher
mortality among individuals with cancer remain incompletely understood. Objective To test …

Statins in cancer prevention and therapy

N Ricco, SJ Kron - Cancers, 2023 - mdpi.com
Simple Summary Retrospective studies of common malignancies such as head and neck
cancer often report lower incidence and/or better outcomes for patients incidentally treated …

[HTML][HTML] Risk of ischaemic cerebrovascular events in head and neck cancer patients is associated with carotid artery radiation dose

ESM van Aken, HP van der Laan, HP Bijl… - Radiotherapy and …, 2021 - Elsevier
Background and purpose Radiotherapy in the head and neck area may cause vascular
damage to the carotid arteries, increasing the risk of anterior circulation ischaemic …

Statin use and risk of vascular events among cancer patients after radiotherapy to the thorax, head, and neck

J Boulet, J Peña, EA Hulten, TG Neilan… - Journal of the …, 2019 - Am Heart Assoc
Background This study aimed to explore whether statins reduce radiation‐induced vascular
complications in cancer patients postradiotherapy to the thorax, head, and neck. Methods …

New therapeutic insights into radiation-induced myocardial fibrosis

CX Ma, XK Zhao, YD Li - Therapeutic advances in chronic …, 2019 - journals.sagepub.com
Radiation therapy (RT) for the treatment of thoracic tumors causes radiation-induced heart
disease (RIHD). Radiation-induced myocardial fibrosis (RIMF) is both an acute and chronic …

Short‐Term Statin Treatment Reduces, and Long‐Term Statin Treatment Abolishes, Chronic Vascular Injury by Radiation Therapy

K Ait‐Aissa, X Guo, M Klemmensen, D Juhr… - Journal of the …, 2024 - ahajournals.org
Background The incidental use of statins during radiation therapy has been associated with
a reduced long‐term risk of developing atherosclerotic cardiovascular disease. We …

Statin use reduces radiation-induced stroke risk in advanced nasopharyngeal carcinoma patients

CY Lin, CL Chang, KC Lin, WM Chen, BC Shia… - Radiotherapy and …, 2024 - Elsevier
Objective This cohort study aimed to evaluate the impact of statin use on ischemic stroke risk
in patients with advanced nasopharyngeal carcinoma (NPC) undergoing standard …

Advanced imaging modalities to detect cardiotoxicity

M Awadalla, MZO Hassan, RM Alvi… - Current problems in cancer, 2018 - Elsevier
Recent advances in cancer treatments have significantly improved survival rates,
reemphasizing the focus on reducing the potential complications associated with some …