Severe sepsis and septic shock are the primary causes of multiple organ dysfunction
syndrome (MODS), which is the most frequent cause of death in intensive care unit patients …

Renal replacement therapy (RRT) has evolved from the concept that we need to treat the
dysfunction of a single organ (the kidney). As intensive care units have become more and …

Bacterial sepsis is a serious clinical condition that can lead to multiple organ dysfunction
and death despite timely treatment with antibiotics and fluid resuscitation. We have …

A potential application of the continuous renal replacement therapies is the extracorporeal
removal of inflammatory mediators in septic patients. Cytokine elimination with continuous …

Objective: The impact of continuous venovenous hemofiltration on sepsis-induced multiple
organ failure severity is controversial. We sought to assess the effect of early application of …

Background Severe complicated intra-abdominal sepsis (SCIAS) has an increasing
incidence with mortality rates over 80% in some settings. Mortality typically results from …

Acute renal failure (ARF) is a well known complication of severe burns and is an important
factor leading to an increase in mortality. In order to analyze possible pathogenetic and …

Background Severe complicated intra-abdominal sepsis (SCIAS) has an increasing
incidence with mortality rates over 80% in some settings. Mortality typically results from …

In the setting of intensive care, patients with acute renal failure often present a clinical
picture of the systemic inflammatory response syndrome (SIRS). SIRS can be caused by …

Sepsis is an adverse systemic inflammatory response caused by microbial infection in
blood. This paper reports a simple microfluidic approach for intrinsic, non-specific removal of …