Co-infections, inflammation and oncogenesis: future directions for EBV research
AB Rickinson - Seminars in cancer biology, 2014 - Elsevier
Epstein–Barr virus (EBV) is aetiologically linked to a wide range of human tumours. Some
arise as accidents of the virus' lifestyle in its natural niche, the B lymphoid system; these …
arise as accidents of the virus' lifestyle in its natural niche, the B lymphoid system; these …
Parasite infection, carcinogenesis and human malignancy
Cancer may be induced by many environmental and physiological conditions. Infections
with viruses, bacteria and parasites have been recognized for years to be associated with …
with viruses, bacteria and parasites have been recognized for years to be associated with …
β-Cell–specific CD8 T cell phenotype in type 1 diabetes reflects chronic autoantigen exposure
Autoreactive CD8 T cells play a central role in the destruction of pancreatic islet β-cells that
leads to type 1 diabetes, yet the key features of this immune-mediated process remain …
leads to type 1 diabetes, yet the key features of this immune-mediated process remain …
PD-1/CTLA-4 blockade inhibits Epstein-Barr virus-induced lymphoma growth in a cord blood humanized-mouse model
Epstein-Barr virus (EBV) infection causes B cell lymphomas in humanized mouse models
and contributes to a variety of different types of human lymphomas. T cells directed against …
and contributes to a variety of different types of human lymphomas. T cells directed against …
Early virological and immunological events in asymptomatic Epstein-Barr virus infection in African children
S Jayasooriya, TI De Silva, J Njie-jobe… - PLoS …, 2015 - journals.plos.org
Epstein-Barr virus (EBV) infection often occurs in early childhood and is asymptomatic.
However, if delayed until adolescence, primary infection may manifest as acute infectious …
However, if delayed until adolescence, primary infection may manifest as acute infectious …
A New Hope for CD56negCD16pos NK Cells as Unconventional Cytotoxic Mediators: An Adaptation to Chronic Diseases
Natural Killer (NK) cells play an essential role in antiviral and anti-tumoral immune
responses. In peripheral blood, NK cells are commonly classified into two major subsets …
responses. In peripheral blood, NK cells are commonly classified into two major subsets …
Malaria—how this parasitic infection aids and abets EBV-associated Burkitt lymphomagenesis
AM Moormann, JA Bailey - Current opinion in virology, 2016 - Elsevier
Highlights•Immunity in young children is functionally and phenotypically different than
adults.•Chronic malaria increases EBV load that then impairs anti-viral immune …
adults.•Chronic malaria increases EBV load that then impairs anti-viral immune …
Poorly cytotoxic terminally differentiated CD56negCD16pos NK cells accumulate in Kenyan children with Burkitt lymphomas
CS Forconi, CP Cosgrove… - Blood …, 2018 - ashpublications.org
Natural killer (NK) cells are critical for restricting viral infections and mediating tumor
immunosurveillance. Epstein-Barr virus (EBV) and Plasmodium falciparum malaria are …
immunosurveillance. Epstein-Barr virus (EBV) and Plasmodium falciparum malaria are …
Controlled human malaria infection leads to long-lasting changes in innate and innate-like lymphocyte populations
Animal model studies highlight the role of innate-like lymphocyte populations in the early
inflammatory response and subsequent parasite control following Plasmodium infection. IFN …
inflammatory response and subsequent parasite control following Plasmodium infection. IFN …
Burkitt's lymphoma
R Rochford, AM Moormann - Epstein Barr Virus Volume 1: One Herpes …, 2015 - Springer
Endemic Burkitt's lymphoma (BL) remains the most prevalent pediatric cancer in sub-
Saharan Africa even though it was the first human cancer with a viral etiology described over …
Saharan Africa even though it was the first human cancer with a viral etiology described over …