The limbic system describes a complex of brain structures central for memory, learning, as
well as goal directed and emotional behavior. In addition to pathological studies, recent …

Parkinson's disease (PD) can be classified into an akinetic-rigid (AR) and a tremor-dominant
(TD) subtype based on predominant motor symptoms. Patients with different motor subtypes …

Cognitive dysfunction constitutes a core characteristic of schizophrenia spectrum disorders
(SZ). Specifically, deficits in updating generative models (ie, cognitive flexibility) and …

The brain's sensitivity to and accentuation of unpredicted over predicted sensory signals
plays a fundamental role in learning. According to recent theoretical models of the predictive …

Background Manifold cognitive deficits have been reported in schizophrenia spectrum
disorders, including disturbances in flexible updating to altered circumstances as well as …

Genetic variations affecting dopaminergic neuromodulation such as the DRD2/ANKK1 and
the COMT Val158Met polymorphisms contribute to goal-directed behavior that requires a …

Resumen en español La flexibilidad del comportamiento es una respuesta que se relaciona
con la habilidad para utilizar las señales ambientales (retroalimentación ambiental) para …