Molecular mechanism of diabetic neuropathy and its pharmacotherapeutic targets

S Dewanjee, S Das, AK Das, N Bhattacharjee… - European journal of …, 2018 - Elsevier
Diabetic neuropathy is regarded as one of the most debilitating outcomes of diabetes
mellitus and may cause pain, decreased motility, and even amputation. Diabetic neuropathy …

Diabetic neuropathy: clinical manifestations and current treatments

BC Callaghan, HT Cheng, CL Stables… - The lancet …, 2012 - thelancet.com
Diabetic peripheral neuropathy is a prevalent, disabling disorder. The most common
manifestation is distal symmetrical polyneuropathy (DSP), but many patterns of nerve injury …

Oral and topical treatment of painful diabetic polyneuropathy: practice guideline update summary: report of the AAN guideline subcommittee

R Price, D Smith, G Franklin, G Gronseth, M Pignone… - Neurology, 2022 - AAN Enterprises
Objective To update the 2011 American Academy of Neurology (AAN) guideline on the
treatment of painful diabetic neuropathy (PDN) with a focus on topical and oral medications …

The evidence for pharmacological treatment of neuropathic pain

NB Finnerup, SH Sindrup, TS Jensen - Pain, 2010 - Elsevier
Randomized, double-blind, placebo-controlled trials on neuropathic pain treatment are
accumulating, so an updated review of the available evidence is needed. Studies were …

Evidence-based guideline: treatment of painful diabetic neuropathy: report of the American Academy of Neurology, the American Association of Neuromuscular and …

V Bril, J England, GM Franklin, M Backonja, J Cohen… - Pm&r, 2011 - Elsevier
Objective To develop a scientifically sound and clinically relevant evidence-based guideline
for the treatment of painful diabetic neuropathy (PDN). Methods We performed a systematic …

Algorithm for neuropathic pain treatment: an evidence based proposal

NB Finnerup, M Otto, HJ McQuay, TS Jensen… - Pain, 2005 - Elsevier
New studies of the treatment of neuropathic pain have increased the need for an updated
review of randomized, double-blind, placebo-controlled trials to support an evidence based …

EFNS guidelines on pharmacological treatment of neuropathic pain

N Attal, G Cruccu, M Haanpää… - European journal of …, 2006 - Wiley Online Library
Neuropathic pain treatment remains unsatisfactory despite a substantial increase in the
number of trials. This EFNS Task Force aimed at evaluating the existing evidence about the …

Diabetic neuropathy and oxidative stress: therapeutic perspectives

A Hosseini, M Abdollahi - Oxidative medicine and cellular …, 2013 - Wiley Online Library
Diabetic neuropathy (DN) is a widespread disabling disorder comprising peripheral
nerves′ damage. DN develops on a background of hyperglycemia and an entangled …

Alcoholic neuropathy: possible mechanisms and future treatment possibilities

K Chopra, V Tiwari - British journal of clinical pharmacology, 2012 - Wiley Online Library
Chronic alcohol consumption produces painful peripheral neuropathy for which there is no
reliable successful therapy, mainly due to lack of understanding of its pathobiology …

Neuropathic pain

LA Zilliox - CONTINUUM: Lifelong Learning in Neurology, 2017 - journals.lww.com
Abstract Purpose of Review: Neuropathic pain is a frequently encountered condition that is
often resistant to treatment and is associated with poor patient satisfaction of their treatment …