The antibacterial activity of fluoroquinolone derivatives: An update (2018–2021)

Y Jia, L Zhao - European journal of medicinal chemistry, 2021 - Elsevier
Bacterial infection is amongst the most common diseases in community and hospital
settings. Fluoroquinolones, exerting the antibacterial activity through binding to type II …

DataWarrior: An evaluation of the open-source drug discovery tool

E López-López, JJ Naveja… - Expert Opinion on Drug …, 2019 - Taylor & Francis
Introduction: DataWarrior is open and interactive software for data analysis and visualization
that integrates well-established and novel chemoinformatics algorithms in a single …

Genetic Variations in the Purinergic P2X7 Receptor Are Associated with the Immune Response to Ocular Toxoplasmosis in Colombia

CA Naranjo-Galvis, R McLeod, JE Gómez-Marín… - Microorganisms, 2023 - mdpi.com
Ocular toxoplasmosis (OT) is characterized by inflammation within the eye and is the most
recognized clinical manifestation of toxoplasmosis. The objective of this study was to identify …

Identification of novel drug targets in Porphyromonas gingivalis and proposing inhibitors against acetate kinase using structure-based virtual screening

H Kalhor, NN Goodarzi, H Rahimi, F Firoozeh… - Process …, 2023 - Elsevier
Porphyromonas gingivalis is the conductor of the orchestration of periodontium
inflammation. Considering that a wide range of antibiotics have lost their activities in the last …

Search of Allosteric Inhibitors and Associated Proteins of an AKT-like Kinase from Trypanosoma cruzi

R Ochoa, C Rocha-Roa, M Marín-Villa… - International Journal of …, 2018 - mdpi.com
Proteins associated to the PI3K/AKT/mTOR signaling pathway are widely used targets for
cancer treatment, and in recent years they have also been evaluated as putative targets in …

Protein targets of thiazolidinone derivatives in Toxoplasma gondii and insights into their binding to ROP18

D Molina, R Cossio-Pérez, C Rocha-Roa, L Pedraza… - BMC genomics, 2018 - Springer
Background Thiazolidinone derivatives show inhibitory activity (IC 50) against the
Toxoplasma gondii parasite, as well as high selectivity with high therapeutic index. To …

[HTML][HTML] Do fluoroquinolone agents produce therapeutic benefits or harmful effects in patients with periodontitis? A systematic review and meta-analysis

SA Romo, F Martinez-Morales… - Dental and Medical …, 2021 - dmp.umw.edu.pl
The adjunctive use of fluoroquinolone (FQ) agents in patients with periodontitis produces
contradictory results. There has been no meta-analysis performed based on the evaluations …

Evaluación in vitro del efecto de nuevas Tiazolidinonas sobre la invasión y crecimiento del parásito Toxoplasma gondii

DA Molina Lara - 2020 - bdigital.uniquindio.edu.co
El tratamiento convencional para la toxoplasmosis es una mezcla entre pirimetamina y
sulfadiazina, pero esta quimioterapia presenta efectos secundarios severos. Algunos …

[PDF][PDF] Evaluación in vitro del efecto de nuevas Tiazolidinonas sobre la invasión y crecimiento del parásito Toxoplasma gondii

DAM Lara - 2020 - bdigital.uniquindio.edu.co
Evaluación in vitro del efecto de nuevas Tiazolidinonas sobre la invasión y crecimiento del
parásito Toxoplasma gondii Diego Page 1 i Evaluación in vitro del efecto de nuevas …