The paramyxovirus family has a genome consisting of a single strand of negative sense
RNA. This genome acts as a template for two distinct processes: transcription to generate …

Interferon‐stimulated gene 20 kDa protein (ISG20) is a relatively understudied antiviral
protein capable of inhibiting a broad spectrum of viruses. ISG20 exhibits strong RNase …

Human respiratory syncytial virus (RSV) is an enveloped, nonsegmented negative-strand
RNA virus of family Paramyxoviridae. RSV is the most complex member of the family in …

The large (L) proteins of non-segmented, negative-strand RNA viruses, a group that
includes Ebola and rabies viruses, catalyze RNA-dependent RNA polymerization with viral …

Many flaviviruses are significant human pathogens. No effective antiviral therapy is currently
available for treatment of flavivirus infections. Development of antiviral treatment against …

Mononegavirales, known as nonsegmented negative-sense (NNS) RNA viruses, are a class
of pathogenic and sometimes deadly viruses that include rabies virus (RABV), human …

The cell intrinsic antiviral response of multicellular organisms developed over millions of
years and critically relies on the ability to sense and eliminate viral nucleic acids. Here we …

The nonsegmented, negative-strand RNA viruses (nsNSVs), also known as the order
Mononegavirales, have a genome consisting of a single strand of negative-sense RNA …

Interferons induce cell-intrinsic responses associated with resistance to viral infection. To
overcome the suppressive action of interferons and their effectors, viruses have evolved …

Nonsegmented negative-sense (NNS) RNA viruses cap their mRNA by an unconventional
mechanism. Specifically, 5′ monophosphate mRNA is transferred to GDP derived from …