Lung cancer cells and their sensitivity/resistance to cisplatin chemotherapy: Role of microRNAs and upstream mediators

M Ashrafizadeh, A Zarrabi, K Hushmandi, F Hashemi… - Cellular signalling, 2021 - Elsevier
Cisplatin (CP) is a well-known chemotherapeutic agent with excellent clinical effects. The
anti-tumor activity of CP has been demonstrated in different cancers such as breast, cervical …

Cardiolipin, the mitochondrial signature lipid: Implication in cancer

ST Ahmadpour, K Mahéo, S Servais, L Brisson… - International journal of …, 2020 - mdpi.com
Cardiolipins (CLs) are specific phospholipids of the mitochondria composing about 20% of
the inner mitochondria membrane (IMM) phospholipid mass. Dysregulation of CL …

In search of the holy grail: toward a unified hypothesis on mitochondrial dysfunction in age-related diseases

J Zhang, Y Shi - Cells, 2022 - mdpi.com
Cardiolipin (CL) is a mitochondrial signature phospholipid that plays a pivotal role in
mitochondrial dynamics, membrane structure, oxidative phosphorylation, mtDNA …

The role of altered mitochondrial metabolism in thyroid cancer development and mitochondria-targeted thyroid cancer treatment

SA Dabravolski, NG Nikiforov, AD Zhuravlev… - International Journal of …, 2021 - mdpi.com
Thyroid cancer (TC) is the most common type of endocrine malignancy. Tumour formation,
progression, and metastasis greatly depend on the efficacy of mitochondria—primarily, the …

Formins in human disease

L Labat-de-Hoz, MA Alonso - Cells, 2021 - mdpi.com
Almost 25 years have passed since a mutation of a formin gene, DIAPH1, was identified as
being responsible for a human inherited disorder: a form of sensorineural hearing loss …

Role of formin INF2 in human diseases

Y Zhao, H Zhang, H Wang, M Ye, X Jin - Molecular Biology Reports, 2022 - Springer
Formin proteins catalyze actin nucleation and microfilament polymerization. Inverted formin
2 (INF2) is an atypical diaphanous-related formin characterized by polymerization and …

Identification of disulfidptosis-associated genes and characterization of immune cell infiltration in thyroid carcinoma

S Song, J Zhou, L Zhang, Y Sun, Q Zhang… - Aging (Albany …, 2024 - pmc.ncbi.nlm.nih.gov
Objective: The primary objective of this study is to conduct a comprehensive screening and
analysis of differentially expressed genes related to disulfidoptosis (DEDRGs) in thyroid …

Investigation of common genetic risk factors between thyroid traits and breast cancer

EA Lucotte, Y Asgari, PE Sugier… - Human Molecular …, 2024 - academic.oup.com
Breast cancer (BC) risk is suspected to be linked to thyroid disorders, however observational
studies exploring the association between BC and thyroid disorders gave conflicting results …

Melatonin attenuates TNF‐α‐mediated hepatocytes damage via inhibiting mitochondrial stress and activating the Akt‐Sirt3 signaling pathway

J Song, C Lu, W Zhao, X Shao - Journal of Cellular Physiology, 2019 - Wiley Online Library
The role of mitochondrial dysfunction and its molecular mechanism in inflammation‐induced
acute liver failure (ALF) remain unknown. Despite the numerous studies performed to date …

The formin-like regulates innate immunity and antibacterial immune responses in Scylla paramamosain

Y Li, Y Zhang, F Zhu - Aquaculture, 2025 - Elsevier
The formin family of proteins, recognized for their evolutionary conservation across species,
plays a pivotal role in the regulation of actin polymerization, thereby influencing cellular …