The application of next-generation sequencing to study congenital heart disease (CHD) is
increasingly providing new insights into the causes and mechanisms of this prevalent birth …

The electromechanical function of the heart involves complex, coordinated activity over time
and space. Life-threatening cardiac arrhythmias arise from asynchrony in these space–time …

The adult zebrafish heart has a high capacity for regeneration following injury. However, the
composition of the regenerative niche has remained largely elusive. Here, we dissected the …

The lateral plate mesoderm (LPM) forms the progenitor cells that constitute the heart and
cardiovascular system, blood, kidneys, smooth muscle lineage and limb skeleton in the …

Mechanical forces are well known for modulating heart valve developmental programs. Yet,
it is still unclear how genetic programs and mechanosensation interact during heart valve …

Standard zebrafish transgenesis involves random transgene integration with resource-
intensive screening. While phiC31 integrase–based attP/attB recombination has streamlined …

The current focus on cardiovascular research reflects society's concerns regarding the
alarming incidence of cardiac-related diseases and mortality in the industrialized world and …

Extensive studies have shown how bilateral symmetry of the vertebrate embryo is broken
during early development, resulting in a molecular left-right bias in the mesoderm. However …

Adult tissue-specific stem cells play a dominant role in tissue homeostasis and regeneration.
Various in vivo markers of adult tissue-specific stem cells have been increasingly reported …

Glyphosate (GLY) is the most widely used broad-spectrum, non-selective herbicide in the
world, whose main degradation product is aminomethyl phosphonic acid (AMPA). Because …