Wolbachia and the biological control of mosquito‐borne disease

I Iturbe‐Ormaetxe, T Walker, SL O'Neill - EMBO reports, 2011 - embopress.org
Mosquito‐borne diseases such as malaria, dengue fever and filariasis cause an enormous
health burden to people living in tropical and subtropical regions of the world. Despite years …

Beyond insecticides: new thinking on an ancient problem

EA McGraw, SL O'neill - Nature Reviews Microbiology, 2013 - nature.com
Vector-borne disease is one of the greatest contributors to human mortality and morbidity
throughout the tropics. Mosquito-transmitted diseases such as malaria, dengue, yellow fever …

Impact of Wolbachia on Infection with Chikungunya and Yellow Fever Viruses in the Mosquito Vector Aedes aegypti

AF Van Den Hurk, S Hall-Mendelin… - PLoS neglected …, 2012 - journals.plos.org
Incidence of disease due to dengue (DENV), chikungunya (CHIKV) and yellow fever (YFV)
viruses is increasing in many parts of the world. The viruses are primarily transmitted by …

Field evaluation of the establishment potential of wmelpop Wolbachia in Australia and Vietnam for dengue control

TH Nguyen, HL Nguyen, TY Nguyen, SN Vu, ND Tran… - Parasites & vectors, 2015 - Springer
Abstract Background Introduced Wolbachia bacteria can influence the susceptibility of
Aedes aegypti mosquitoes to arboviral infections as well as having detrimental effects on …

Wolbachia uses a host microRNA to regulate transcripts of a methyltransferase, contributing to dengue virus inhibition in Aedes aegypti

G Zhang, M Hussain, SL O'Neill… - Proceedings of the …, 2013 - National Acad Sciences
The endosymbiont Wolbachia is common among insects and known for the reproductive
manipulations it exerts on hosts as well as inhibition of virus replication in their hosts …

Assessment of bacterial diversity in the cattle tick Rhipicephalus (Boophilus) microplusthrough tag-encoded pyrosequencing

R Andreotti, AA Pérez de León, SE Dowd… - BMC microbiology, 2011 - Springer
Background Ticks are regarded as the most relevant vectors of disease-causing pathogens
in domestic and wild animals. The cattle tick, Rhipicephalus (Boophilus) microplus, hinders …

Wolbachia Reduces the Transmission Potential of Dengue-Infected Aedes aegypti

YH Ye, AM Carrasco, FD Frentiu… - PLoS neglected …, 2015 - journals.plos.org
Background Dengue viruses (DENV) are the causative agents of dengue, the world's most
prevalent arthropod-borne disease with around 40% of the world's population at risk of …

Dynamics of the “Popcorn” Wolbachia Infection in Outbred Aedes aegypti Informs Prospects for Mosquito Vector Control

HL Yeap, P Mee, T Walker, AR Weeks, SL O'Neill… - Genetics, 2011 - academic.oup.com
Forty percent of the world's population is at risk of contracting dengue virus, which produces
dengue fever with a potentially fatal hemorrhagic form. The w MelPop Wolbachia infection of …

Wolbachia-Mediated Resistance to Dengue Virus Infection and Death at the Cellular Level

FD Frentiu, J Robinson, PR Young, EA McGraw… - PloS one, 2010 - journals.plos.org
Background Dengue is currently the most important arthropod-borne viral disease of
humans. Recent work has shown dengue virus displays limited replication in its primary …

Competition for Amino Acids Between Wolbachia and the Mosquito Host, Aedes aegypti

EP Caragata, E Rancès, SL O'Neill, EA McGraw - Microbial ecology, 2014 - Springer
The endosymbiont Wolbachia represents a promising method of dengue control, as it
reduces the ability of the primary vector, the mosquito Aedes aegypti, to transmit viruses …