The persistent COVID-19 pandemic since 2020 has brought an enormous public health
burden to the global society and is accompanied by various evolution of the virus genome …

COVID-19, the disease caused by SARS-CoV-2, has claimed approximately 5 million lives
and 257 million cases reported globally. This virus and disease have significantly affected …

Abstract The SARS-CoV-2 Delta variant is currently the dominant circulating strain in the
world. Uncovering the structural basis of the enhanced transmission and altered immune …

The spike protein of SARS-CoV-2 binds to the ACE2 receptor via its receptor-binding
domain (RBD), with the RBD–ACE2 complex presenting an essential molecular target for …

The emergence of SARS-CoV-2 Kappa and Beta variants with enhanced transmissibility
and resistance to neutralizing antibodies has created new challenges for the control of the …

Coronavirus spike proteins mediate receptor binding and membrane fusion, making them
prime targets for neutralizing antibodies. In the cases of severe acute respiratory syndrome …

The D614G mutation in the spike protein of SARS-CoV-2 alters the fitness of the virus,
leading to the dominant form observed in the COVID-19 pandemic. However, the molecular …

The COVID‐19 pandemic has caused an unprecedented health crisis and economic burden
worldwide. Its etiological agent SARS‐CoV‐2, a new virus in the coronavirus family, has …

Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has brought an unprecedented public health crisis …

The repeat emergence of SARS-CoV-2 variants of concern (VoC) with decreased
susceptibility to vaccine-elicited antibodies highlights the need to develop next-generation …