The role of choline in neurodevelopmental disorders—A narrative review focusing on ASC, ADHD and dyslexia

E Derbyshire, M Maes - Nutrients, 2023 - mdpi.com
Neurodevelopmental disorders appear to be rising in prevalence, according to the recent
Global Burden of Disease Study. This rise is likely to be multi-factorial, but the role of certain …

Early life nutrition and brain development: breakthroughs, challenges and new horizons

MK Georgieff - Proceedings of the Nutrition Society, 2023 - cambridge.org
The role of early life nutrition's impact on relevant health outcomes across the lifespan laid
the foundation for the field titled the developmental origins of health and disease. Studies in …

Quantitative omics analyses of NCOA4 deficiency reveal an integral role of ferritinophagy in iron homeostasis of hippocampal neuronal HT22 cells

EF Bengson, CA Guggisberg, TW Bastian… - Frontiers in …, 2023 - frontiersin.org
Introduction Neurons require iron to support their metabolism, growth, and differentiation, but
are also susceptible to iron-induced oxidative stress and cytotoxicity. Ferritin, a cytosolic iron …

Differential early mechanistic frontal lobe responses to choline chloride and soy isoflavones in an experimental model of fetal alcohol spectrum disorder

SM de la Monte, M Tong, B Delikkaya - International journal of molecular …, 2023 - mdpi.com
Fetal alcohol spectrum disorder (FASD) is the most common preventable cause of
neurodevelopmental defects, and white matter is a major target of ethanol neurotoxicity …

Sex-specific effects of early-life iron deficiency and prenatal choline treatment on adult rat hippocampal transcriptome

SX Liu, TK Fredrickson, N Calixto Mancipe… - Nutrients, 2023 - mdpi.com
Background: Fetal-neonatal iron deficiency (ID) causes long-term neurocognitive and
affective dysfunctions. Clinical and preclinical studies have shown that early-life ID produces …

Poria cocos (Schw.) Wolf, a Traditional Chinese Edible Medicinal Herb, Promotes Neuronal Differentiation, and the Morphological Maturation of Newborn Neurons in …

X Jiang, Z Hu, X Qiu, L Wu, R Zhou, Y Yang, X Xiang - Molecules, 2023 - mdpi.com
Neurogenesis in the adult brain comprises the entire set of events of neuronal development.
It begins with the division of precursor cells to form a mature, integrated, and functioning …

Cellular Iron Deficiency Disrupts Thyroid Hormone Regulated Gene Expression in Developing Hippocampal Neurons

TR Monko, EH Tripp, SE Burr, KN Gunderson… - The Journal of …, 2024 - Elsevier
Background Developing neurons have high thyroid hormone and iron requirements to
support their metabolically demanding growth. Early-life iron and thyroid-hormone …

Application of Choline for Treatment of Traumatic Brain Injury

F Rachidi, H Ouaki, R Hilali, A Azzouz, YAEH Ali… - Nutrition and Traumatic …, 2024 - Springer
The primary and secondary injuries are the phases of the pathophysiology of traumatic brain
injury (TBI). Primary injury happens when the brain is subjected to an external force that …

Growth Factor Signaling in Fetal Alcohol Spectrum Disorders and the Impact of Choline

S Liang - 2024 - search.proquest.com
Prenatal alcohol exposure (PAE) can lead to a wide range of physical and cognitive
impairments classified as fetal alcohol spectrum disorders (FASD). With 1-5% of US school …

Poria cocos (Schw.) Wolf, a Traditional Chinese Edible Medicinal Herb, Promotes Neuronal Differentiation and Maturation of Neural Stem/Progenitor Cells

X Jiang, Z Hu, X Qiu, L Wu, R Zhou, Y Yang, X Xiang - 2023 - preprints.org
Neurogenesis in the adult brain plays a major role in the cognitive ability of animals
including learning and memory. Poria cocos (Schw.) Wolf (P. cocos) has been known as a …