Progress in the diagnosis of leishmaniases depends on the development of effective
methods and the discovery of suitable biomarkers. We propose firstly an update …

▪ Abstract RNA editing can be broadly defined as any site-specific alteration in an RNA
sequence that could have been copied from the template, excluding changes due to …

Double-stranded RNA (dsRNA) recently has been shown to give rise to genetic interference
in Caenorhabditis elegans and also is likely to be the basis for phenotypic cosuppression in …

The neutral theory often is presented as a theory of``noise''or silent changes at an
isolated``molecular level,''relevant to marking the steady pace of divergence, but not to the …

A recent issue of Science (Vol. 283, March 5, 1999) had a cover showing a mitochondrion
and a headline inside asserting thatMitochondria Make A Comeback'. Why the revival of …

The term RNA editing describes those molecular processes in which the information content
is altered in an RNA molecule. To date such changes have been observed in tRNA, rRNA …

The genetic code has been proposed to be a 'frozen accident,'but the discovery of
alternative genetic codes over the past four decades has shown that it can evolve to some …

This review attempts to summarize our present state of knowledge of mitochondria in
relation to a number of areas of biology, and to indicate where future research might be …

Two different RNA editing systems have been described in the kinetoplast-mitochondrion of
trypanosomatid protists. The first involves the precise insertion and deletion of U residues …

Plastid transcripts can be subject to an RNA processing mechanism changing the identity of
individual nucleotides and thus altering the information content of the mRNA. This …