Artificial intelligence for digital and computational pathology

AH Song, G Jaume, DFK Williamson, MY Lu… - Nature Reviews …, 2023 - nature.com
Advances in digitizing tissue slides and the fast-paced progress in artificial intelligence,
including deep learning, have boosted the field of computational pathology. This field holds …

Computational pathology in cancer diagnosis, prognosis, and prediction–present day and prospects

G Verghese, JK Lennerz, D Ruta, W Ng… - The Journal of …, 2023 - Wiley Online Library
Computational pathology refers to applying deep learning techniques and algorithms to
analyse and interpret histopathology images. Advances in artificial intelligence (AI) have led …

Open and reusable deep learning for pathology with WSInfer and QuPath

JR Kaczmarzyk, A O'Callaghan, F Inglis, S Gat… - NPJ Precision …, 2024 - nature.com
Digital pathology has seen a proliferation of deep learning models in recent years, but many
models are not readily reusable. To address this challenge, we developed WSInfer: an open …

Digital staining in optical microscopy using deep learning-a review

L Kreiss, S Jiang, X Li, S Xu, KC Zhou, KC Lee… - PhotoniX, 2023 - Springer
Until recently, conventional biochemical staining had the undisputed status as well-
established benchmark for most biomedical problems related to clinical diagnostics …

RedTell: an AI tool for interpretable analysis of red blood cell morphology

A Sadafi, M Bordukova, A Makhro, N Navab… - Frontiers in …, 2023 - frontiersin.org
Introduction: Hematologists analyze microscopic images of red blood cells to study their
morphology and functionality, detect disorders and search for drugs. However, accurate …

Hepatocellular carcinoma immune microenvironment analysis: A comprehensive assessment with computational and classical pathology

C Ercan, SL Renne, L Di Tommaso, CKY Ng… - Clinical Cancer …, 2024 - aacrjournals.org
Purpose: The spatial variability and clinical relevance of the tumor immune
microenvironment (TIME) are still poorly understood for hepatocellular carcinoma (HCC). In …

[HTML][HTML] Evaluation of deep learning training strategies for the classification of bone marrow cell images

S Glüge, S Balabanov, VH Koelzer, T Ott - Computer Methods and …, 2024 - Elsevier
Abstract Background and Objective: The classification of bone marrow (BM) cells by light
microscopy is an important cornerstone of hematological diagnosis, performed thousands of …

Can virtual staining for high-throughput screening generalize?

S Tonks, C Nguyen, S Hood, R Musso… - arXiv preprint arXiv …, 2024 - arxiv.org
The large volume and variety of imaging data from high-throughput screening (HTS) in the
pharmaceutical industry present an excellent resource for training virtual staining models …

[HTML][HTML] Historical perspective and future directions: computational science in immuno-oncology

CA Ricker, K Meli, EM Van Allen - Journal for Immunotherapy of …, 2024 - ncbi.nlm.nih.gov
Immuno-oncology holds promise for transforming patient care having achieved durable
clinical response rates across a variety of advanced and metastatic cancers. Despite these …

[HTML][HTML] Transferable automatic haematological cell classification: overcoming data limitations with self-supervised learning

L Wenderoth, AM Asemissen, F Modemann… - Computer Methods and …, 2024 - Elsevier
Abstract Background and Objective Classification of peripheral blood and bone marrow cells
is critical in the diagnosis and monitoring of hematological disorders. The development of …