Adolescent nicotine induces persisting changes in development of neural connectivity. A
large number of brain changes occur during adolescence as the CNS matures. These …

Modern life poses many threats to good-quality sleep, challenging brain health across the
lifespan. Curtailed or fragmented sleep may be particularly damaging during adolescence …

The mechanisms underpinning concussion, traumatic brain injury, and chronic traumatic
encephalopathy, and the relationships between these disorders, are poorly understood. We …

Among the 3.5 million annual new head injury cases is a subpopulation of children and
young adults who experience repeated traumatic brain injury (TBI). The duration of …

Social experiences during youth are thought to be critical for proper social and cognitive
development. Conversely, social insults during development can cause long-lasting …

Alzheimer's disease is caused by increased production or reduced clearance of amyloid-β,
which results in the formation amyloid-β plaques and triggers a cascade of downstream …

Upon retrieval, fear memories are rendered labile and prone to modification, necessitating a
restabilization process of reconsolidation to persist further. This process is also crucial for …

It is well established that physical exercise can enhance hippocampal-dependent forms of
learning and memory in laboratory animals, commensurate with increases in hippocampal …

The field of proteomics is undergoing rapid development in a number of different areas
including improvements in mass spectrometric platforms, peptide identification algorithms …

Postsynaptic proteins play crucial roles in synaptic function and plasticity. During brain
development, alterations in synaptic number, shape, and stability occur, known as synapse …