Interferon-related depression: a primer on mechanisms, treatment, and prevention of a common clinical problem

E Franscina Pinto, C Andrade - Current neuropharmacology, 2016 - ingentaconnect.com
Background: Depression is among the commonest of psychiatric disorders, and
inflammatory mechanisms have been suggested to play a role in its pathophysiology …

Inflammatory markers are associated with decreased psychomotor speed in patients with major depressive disorder

DR Goldsmith, E Haroon, BJ Woolwine… - Brain, behavior, and …, 2016 - Elsevier
Previous data have demonstrated that administration of inflammatory cytokines or their
inducers leads to altered basal ganglia function associated with reduced psychomotor …

Interferon-alpha-induced depression: Comparisons between early-and late-onset subgroups and with patients with major depressive disorder

KP Su, HC Lai, CY Peng, WP Su, JPC Chang… - Brain, behavior, and …, 2019 - Elsevier
Abstract Interferon (IFN)-alpha, until recently the standard treatment of hepatitis C virus
(HCV) infection, is associated with a significant risk of major depressive episode (MDE, or …

The level of IL-6 was associated with sleep disturbances in patients with major depressive disorder

M Wang, J Wei, X Yang, P Ni, Y Wang… - Neuropsychiatric …, 2019 - Taylor & Francis
Purpose: Major depression disorder (MDD) was associated with inflammatory processes,
but association results of inflammatory syndrome and MDD were inconsistent. To provide …

Hepatitis C virus eradication improves immediate and delayed episodic memory in patients treated with interferon and ribavirin

MED Barbosa, AL Zaninotto, DF de Campos Mazo… - BMC …, 2017 - Springer
Background Chronic hepatitis C virus (HCV) infection is associated with impairment of
cognitive function and mood disorders. Our aim was to evaluate the impact of sustained …

Factor analyses differentiate clinical phenotypes of idiopathic and interferon-alpha-induced depression

R Whale, R Fialho, AP Field, G Campbell… - Brain, behavior, and …, 2019 - Elsevier
The discovery that prolonged administration of interferon-alpha (a pro-inflammatory
cytokine) readily precipitates depressive symptoms has played a key role in development of …

Assessment of factors associated with the quality of life of patients living with HIV/HCV co-infection

M Pereira, R Fialho - Journal of behavioral medicine, 2016 - Springer
This study compared the quality of life (QoL) of HIV-infected patients with and without
hepatitis C and examined the sociodemographic, HIV-related and psychological symptoms …

Co-infection with HIV associated with reduced vulnerability to symptoms of depression during antiviral treatment for hepatitis C

R Fialho, M Pereira, N Harrison, J Rusted, R Whale - Psychiatry research, 2017 - Elsevier
In this prospective study, we examined new-onset major depressive disorder (MDD) and the
differential expression of depressive symptoms in a sample of 132 HCV mono-infected and …

Drug-induced (medication-induced) depression in neurology practice

EY Ebzeeva, OD Ostroumova… - Neurology …, 2021 - nnp.ima-press.net
One of the depression causes is the use of certain drugs, and in this case, the term drug-
induced depression (DID), medication-induced or iatrogenic depression is used. Symptoms …

A longitudinal study assessing depression in hepatitis C: Does gender play a role in the new-onset depression during interferon-alpha treatment?

R Fialho, M Pereira, Y Gilleece, J Rusted… - Women & …, 2019 - Taylor & Francis
In this prospective study conducted from October 2013 to June 2015 in Brighton, England,
we examined differences between men and women in new-onset major depressive disorder …