The ability of pathogenic fungi to switch between a multicellular hyphal and unicellular yeast
growth form is a tightly regulated process known as dimorphic switching. Dimorphic …

Plants have evolved many strategies for adaptation to extreme environments. Ca2+, acting
as an important secondary messenger in plant cells, is a signaling molecule involved in …

Fungi and antifungal compounds are relevant to the United Nation's Sustainable
Development Goals. However, the modes‐of‐action of antifungals—whether they are …

Many pathogenic fungi are dimorphic and switch between yeast and filamentous states. This
switch alters host-microbe interactions and is critical for pathogenicity. However, in …

Paracoccidioides brasiliensis and P. lutzii are etiologic agents of paracoccidioidomycosis
(PCM), an important endemic mycosis in Latin America. During its evolution, these fungi …

Calcineurin is a highly conserved serine-threonine specific protein phosphatase and was
named based on its discovery as a calcium-and calmodulin-binding protein that is highly …

Calcineurin plays essential roles in virulence and growth of pathogenic fungi and is a target
of the natural products FK 506 and C yclosporine A. In the pathogenic mucoralean fungus M …

Morphological changes are a very common and effective strategy for pathogens to survive in
the mammalian host. During interactions with their host, human pathogenic fungi undergo …

Infections caused by resistant microorganisms often fail to respond to conventional therapy,
resulting in prolonged illness, increased treatment costs and greater risk of death …

The corn smut fungus Ustilago maydis serves as a model species for studying fungal
dimorphism and its role in phytopathogenic development. The pathogen has two growth …