Cleft lip and palate: understanding genetic and environmental influences

MJ Dixon, ML Marazita, TH Beaty… - Nature Reviews Genetics, 2011 - nature.com
Clefts of the lip and/or palate (CLP) are common birth defects of complex aetiology. CLP can
occur in isolation or as part of a broad range of chromosomal, Mendelian or teratogenic …

Orofacial clefts embryology, classification, epidemiology, and genetics

G Nasreddine, J El Hajj… - … Research/Reviews in …, 2021 - Elsevier
Orofacial clefts (OFCs) rank as the second most common congenital birth defect in the
United States after Down syndrome and are the most common head and neck congenital …

Genetics of cleft lip and cleft palate

EJ Leslie, ML Marazita - … Journal of Medical Genetics Part C …, 2013 - Wiley Online Library
Orofacial clefts are common birth defects and can occur as isolated, nonsyndromic events or
as part of Mendelian syndromes. There is substantial phenotypic diversity in individuals with …

Genome-wide analyses of non-syndromic cleft lip with palate identify 14 novel loci and genetic heterogeneity

Y Yu, X Zuo, M He, J Gao, Y Fu, C Qin, L Meng… - Nature …, 2017 - nature.com
Non-syndromic cleft lip with palate (NSCLP) is the most serious sub-phenotype of non-
syndromic orofacial clefts (NSOFC), which are the most common craniofacial birth defects in …

Improving human forensics through advances in genetics, genomics and molecular biology

M Kayser, P De Knijff - Nature Reviews Genetics, 2011 - nature.com
Forensic DNA profiling currently allows the identification of persons already known to
investigating authorities. Recent advances have produced new types of genetic markers …

A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4

TH Beaty, JC Murray, ML Marazita, RG Munger… - Nature …, 2010 - nature.com
Case-parent trios were used in a genome-wide association study of cleft lip with and without
cleft palate. SNPs near two genes not previously associated with cleft lip with and without …

A genome-wide association study identifies five loci influencing facial morphology in Europeans

F Liu, F Van Der Lijn, C Schurmann, G Zhu… - 2012 - journals.plos.org
Inter-individual variation in facial shape is one of the most noticeable phenotypes in
humans, and it is clearly under genetic regulation; however, almost nothing is known about …

[HTML][HTML] Genetic factors influencing risk to orofacial clefts: today's challenges and tomorrow's opportunities

TH Beaty, ML Marazita, EJ Leslie - F1000Research, 2016 - ncbi.nlm.nih.gov
Orofacial clefts include cleft lip (CL), cleft palate (CP), and cleft lip and palate (CLP), which
combined represent the largest group of craniofacial malformations in humans with an …

[图书][B] Veterinary embryology

TA McGeady, PJ Quinn, ES Fitzpatrick, MT Ryan… - 2017 - books.google.com
Veterinary Embryology, 2nd Edition, has been updated to reflect the many changes that
have developed in the field; the text has been fully revised and expanded and is now in full …

A multi-ethnic genome-wide association study identifies novel loci for non-syndromic cleft lip with or without cleft palate on 2p24. 2, 17q23 and 19q13

EJ Leslie, JC Carlson, JR Shaffer… - Human molecular …, 2016 - academic.oup.com
Orofacial clefts (OFCs), which include non-syndromic cleft lip with or without cleft palate
(CL/P), are among the most common birth defects in humans, affecting approximately 1 in …