Medial vascular calcification revisited: review and perspectives

P Lanzer, M Boehm, V Sorribas, M Thiriet… - European heart …, 2014 - academic.oup.com
Vascular calcifications (VCs) are actively regulated biological processes associated with
crystallization of hydroxyapatite in the extracellular matrix and in cells of the media (VCm) or …

Are we close to defining a metabolomic signature of human obesity? A systematic review of metabolomics studies

OD Rangel-Huerta, B Pastor-Villaescusa, A Gil - Metabolomics, 2019 - Springer
Introduction Obesity is a disorder characterized by a disproportionate increase in body
weight in relation to height, mainly due to the accumulation of fat, and is considered a …

High-fat diet induces depression-like behaviour in mice associated with changes in microbiome, neuropeptide Y, and brain metabolome

AM Hassan, G Mancano, K Kashofer… - Nutritional …, 2019 - Taylor & Francis
Objectives: The biological mechanisms linking diet-related obesity and depression remain
unclear. Therefore, we examined the impact of high-fat diet (HFD) on murine behaviour …

Mitochondrial reactive oxygen species mediate lysophosphatidylcholine-induced endothelial cell activation

X Li, P Fang, Y Li, YM Kuo, AJ Andrews… - … , and vascular biology, 2016 - Am Heart Assoc
Objective—Hyperlipidemia-induced endothelial cell (EC) activation is considered as an
initial event responsible for monocyte recruitment in atherogenesis. However, it remains …

Metabolomic insights into the intricate gut microbial–host interaction in the development of obesity and type 2 diabetes

M Palau-Rodriguez, S Tulipani… - Frontiers in …, 2015 - frontiersin.org
Gut microbiota has recently been proposed as a crucial environmental factor in the
development of metabolic diseases such as obesity and type 2 diabetes, mainly due to its …

[HTML][HTML] A metabolomic approach to understanding the metabolic link between obesity and diabetes

S Park, KC Sadanala, EK Kim - Molecules and cells, 2015 - Elsevier
Obesity and diabetes arise from an intricate interplay between both genetic and
environmental factors. It is well recognized that obesity plays an important role in the …

A review of emerging technologies for the management of diabetes mellitus

K Zarkogianni, E Litsa, K Mitsis, PY Wu… - IEEE Transactions …, 2015 - ieeexplore.ieee.org
Objective: High prevalence of diabetes mellitus (DM) along with the poor health outcomes
and the escalated costs of treatment and care poses the need to focus on prevention, early …

Metabolomics–the complementary field in systems biology: a review on obesity and type 2 diabetes

MHA Bakar, MR Sarmidi, KK Cheng, AA Khan… - Molecular …, 2015 - pubs.rsc.org
Metabolomic studies on obesity and type 2 diabetes mellitus have led to a number of
mechanistic insights into biomarker discovery and comprehension of disease progression at …

Metabolomics in diabetic kidney disease: unraveling the biochemistry of a silent killer

M Darshi, B Van Espen, K Sharma - American journal of nephrology, 2016 - karger.com
The development of new therapies for chronic diseases, such as diabetic kidney disease
(DKD), will continue to be hampered by lack of sufficient biomarkers that will provide insights …

Mechanism of action of acupuncture in obesity: a perspective from the hypothalamus

L Wang, CC Yu, J Li, Q Tian, YJ Du - Frontiers in Endocrinology, 2021 - frontiersin.org
Obesity is a prevalent metabolic disease caused by an imbalance in food intake and energy
expenditure. Although acupuncture is widely used in the treatment of obesity in a clinical …