G protein-coupled receptors (GPCRs) are the largest group of cell surface receptors in
humans that signal in response to diverse inputs and regulate a plethora of cellular …

Traumatic brain injury (TBI) is one of the leading causes of death of young people in the
developed world. In the United States alone, 1.7 million traumatic events occur annually …

The plasma membrane in eukaryotic cells contains microdomains that are enriched in
certain glycosphingolipids, gangliosides, and sterols (such as cholesterol) to form …

G protein-coupled receptors (GPCRs) regulate many cellular and physiological processes,
responding to a diverse range of extracellular stimuli including hormones, neurotransmitters …

Signalling pathways involving the vital second messanger, cAMP, impact on most significant
physiological processes. Unsurprisingly therefore, the activation and regulation of cAMP …

G protein-coupled receptors (GPCRs) are organised within the cell membrane into highly
ordered macromolecular complexes along with other receptors and signalling proteins …

Recent advances in the AC (adenylate cyclase)/cAMP field reveal overarching roles for the
ACs. Whereas few processes are unaffected by cAMP in eukaryotes, ranging from the rapid …

Surface recognition and penetration are critical steps in the infection cycle of many plant
pathogenic fungi. In Magnaporthe oryzae, cAMP signaling is involved in surface recognition …

Abstract The Ca 2+ and cAMP/PKA pathways are the primary signaling systems in secretory
epithelia that control virtually all secretory gland functions. Interaction and crosstalk in Ca 2+ …

Spatially restricting cAMP production to discrete subcellular locations permits selective
regulation of specific functional responses. But exactly where and how cAMP signaling is …