Acceptance of clinical artificial intelligence among physicians and medical students: a systematic review with cross-sectional survey

M Chen, B Zhang, Z Cai, S Seery, MJ Gonzalez… - Frontiers in …, 2022 - frontiersin.org
Background Artificial intelligence (AI) needs to be accepted and understood by physicians
and medical students, but few have systematically assessed their attitudes. We investigated …

Attention-based knowledge graph representation learning for predicting drug-drug interactions

X Su, L Hu, Z You, P Hu, B Zhao - Briefings in bioinformatics, 2022 - academic.oup.com
Drug–drug interactions (DDIs) are known as the main cause of life-threatening adverse
events, and their identification is a key task in drug development. Existing computational …

Biomedical knowledge graph embedding with capsule network for multi-label drug-drug interaction prediction

X Su, Z You, D Huang, L Wang, L Wong… - … on Knowledge and …, 2022 - ieeexplore.ieee.org
Drug-drug interaction (DDI) plays an important role in drug development and administration.
Identifying potential DDI effectively is critical for public health since it can avoid adverse drug …

A deep learning method for repurposing antiviral drugs against new viruses via multi-view nonnegative matrix factorization and its application to SARS-CoV-2

X Su, L Hu, Z You, P Hu, L Wang… - Briefings in …, 2022 - academic.oup.com
The outbreak of COVID-19 caused by SARS-coronavirus (CoV)-2 has made millions of
deaths since 2019. Although a variety of computational methods have been proposed to …

A geometric deep learning framework for drug repositioning over heterogeneous information networks

BW Zhao, XR Su, PW Hu, YP Ma… - Briefings in …, 2022 - academic.oup.com
Drug repositioning (DR) is a promising strategy to discover new indicators of approved
drugs with artificial intelligence techniques, thus improving traditional drug discovery and …

A computational approach to drug repurposing using graph neural networks

S Doshi, SP Chepuri - Computers in Biology and Medicine, 2022 - Elsevier
Drug repurposing is an approach to identify new medical indications of approved drugs. This
work presents a graph neural network drug repurposing model, which we refer to as …

Predicting protein-protein interactions using sequence and network information via variational graph autoencoder

X Luo, L Wang, P Hu, L Hu - IEEE/ACM Transactions on …, 2023 - ieeexplore.ieee.org
Protein-protein interactions (PPIs) play a critical role in the proteomics study, and a variety of
computational algorithms have been developed to predict PPIs. Though effective, their …

Advancing drug–target interaction prediction: a comprehensive graph-based approach integrating knowledge graph embedding and ProtBert pretraining

WE Djeddi, K Hermi, S Ben Yahia, G Diallo - BMC bioinformatics, 2023 - Springer
Background The pharmaceutical field faces a significant challenge in validating drug target
interactions (DTIs) due to the time and cost involved, leading to only a fraction being …

A geometric deep learning model for display and prediction of potential drug-virus interactions against SARS-CoV-2

B Das, M Kutsal, R Das - Chemometrics and Intelligent Laboratory Systems, 2022 - Elsevier
Although the coronavirus epidemic spread rapidly with the Omicron variant, it lost its lethality
rate with the effect of vaccine and immunity. The hospitalization and intense demand …

Improving prediction of drug-target interactions based on fusing multiple features with data balancing and feature selection techniques

H Khojasteh, J Pirgazi, A Ghanbari Sorkhi - Plos one, 2023 - journals.plos.org
Drug discovery relies on predicting drug-target interaction (DTI), which is an important
challenging task. The purpose of DTI is to identify the interaction between drug chemical …