Understanding nanoparticle endocytosis to improve targeting strategies in nanomedicine

MS de Almeida, E Susnik, B Drasler… - Chemical society …, 2021 - pubs.rsc.org
Nanoparticles (NPs) have attracted considerable attention in various fields, such as
cosmetics, the food industry, material design, and nanomedicine. In particular, the fast …

Phagocytosis: our current understanding of a universal biological process

E Uribe-Querol, C Rosales - Frontiers in immunology, 2020 - frontiersin.org
Phagocytosis is a cellular process for ingesting and eliminating particles larger than 0.5 μm
in diameter, including microorganisms, foreign substances, and apoptotic cells …

Phagocytosis: a fundamental process in immunity

C Rosales, E Uribe-Querol - BioMed research international, 2017 - Wiley Online Library
One hundred years have passed since the death of Élie Metchnikoff (1845–1916). He was
the first to observe the uptake of particles by cells and realized the importance of this …

[HTML][HTML] Phagocytic function of tumor-associated macrophages as a key determinant of tumor progression control: a review

M Lecoultre, V Dutoit, PR Walker - Journal for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Tumor-associated macrophage (TAM) phagocytic activity is emerging as a new mechanism
to harness for cancer treatment. Currently, many approaches are investigated at the …

Phagocytosis: receptors, signal integration, and the cytoskeleton

SA Freeman, S Grinstein - Immunological reviews, 2014 - Wiley Online Library
Phagocytosis is a remarkably complex and versatile process: it contributes to innate
immunity through the ingestion and elimination of pathogens, while also being central to …

The cell biology of phagocytosis

RS Flannagan, V Jaumouillé… - Annual Review of …, 2012 - annualreviews.org
Engulfment and destruction of invading microorganisms by phagocytosis are critical
components of the innate immune response. In addition, phagocytosis is also required for …

Information processing during phagocytosis

DM Underhill, HS Goodridge - Nature Reviews Immunology, 2012 - nature.com
Phagocytosis—the process by which macrophages, dendritic cells and other myeloid
phagocytes internalize diverse particulate targets—is a key mechanism of innate immunity …

Roles for actin assembly in endocytosis

OL Mooren, BJ Galletta… - Annual review of …, 2012 - annualreviews.org
Endocytosis includes a number of processes by which cells internalize segments of their
plasma membrane, enclosing a wide variety of material from outside the cell. Endocytosis …

Noncanonical autophagy is required for type I interferon secretion in response to DNA-immune complexes

J Henault, J Martinez, JM Riggs, J Tian, P Mehta… - Immunity, 2012 - cell.com
Summary Toll-like receptor-9 (TLR9) is largely responsible for discriminating self from
pathogenic DNA. However, association of host DNA with autoantibodies activates TLR9 …

Theoretical and computational investigations of nanoparticle–biomembrane interactions in cellular delivery

H Ding, Y Ma - Small, 2015 - Wiley Online Library
With the rapid development of nanotechnology, nanoparticles have been widely used in
many applications such as phototherapy, cell imaging, and drug/gene delivery. A better …