Biomaterials that induce immunogenic cell death

D Li, S Liu, Y Ma, S Liu, Y Liu, J Ding - Small Methods, 2023 - Wiley Online Library
The immune system takes part in most physiological and pathological processes of the
body, including the occurrence and development of cancer. Immunotherapy provides a …

Immunopeptides: immunomodulatory strategies and prospects for ocular immunity applications

Y Tang, S Qu, Z Ning, H Wu - Frontiers in Immunology, 2024 - frontiersin.org
Immunopeptides have low toxicity, low immunogenicity and targeting, and broad application
prospects in drug delivery and assembly, which are diverse in application strategies and …

Self‐Splittable Transcytosis Nanoraspberry for NIR‐II Photo‐Immunometabolic Cancer Therapy in Deep Tumor Tissue

L Wang, W Jiang, Y Su, M Zhan, S Peng… - Advanced …, 2022 - Wiley Online Library
Cancer photo‐immunotherapy (CPIT) as an ideal strategy can rapidly release hostile signals
by appropriate dosage of focal laser irradiation to unmask primary tumor immunogenicity …

Pyroptosis induction synergized with IDO inhibition of ternary biomedicine for photodynamic activated tumor immunotherapy

A Chen, N Yang, W Zhang, R Zheng, R Yu… - Chemical Engineering …, 2023 - Elsevier
The development of immunotherapy is seriously limited by the insufficient tumor
immunogenicity and immunosuppressive microenvironment. Pyroptosis is a new form of …

Engineered probiotic Escherichia coli elicits immediate and long-term protection against influenza A virus in mice

L Huang, W Tang, L He, M Li, X Lin, A Hu… - Nature …, 2024 - nature.com
Influenza virus infection remains a major global health problem and requires a universal
vaccine with broad protection against different subtypes as well as a rapid-response vaccine …

A multifunctional CaCO3 bioreactor coated with coordination polymers enhances cancer immunotherapy

W Chen, Y Lu, X Sun, J Leng, S Lin, X He… - Journal of Controlled …, 2024 - Elsevier
Designing effective nanomedicines to induce durable anti-tumor immunity represents a
promising strategy for improving moderate immune stimulation. In this study, we engineered …

USFDA-approved parenteral peptide formulations and excipients: Industrial perspective

S Kumar, SN Sanap, M Vasoya, M Handa… - Journal of Drug Delivery …, 2024 - Elsevier
Parenteral preparations are sterile and non-pyrogenic formulations designed for delivery
into the human or animal body by injection, infusion, or implantation. Peptides are widely …

Photofabrication of fluorescent nanospheres from de novo designed peptides, and their enzyme-responsive dissociation in living cells

S He, X Shu, Z Wang, XW Gao, K Feng, S Yang… - Materials …, 2024 - pubs.rsc.org
Photochemical synthesis stands out as an exceptional approach for the bottom-up
fabrication of functional assemblies using peptide building blocks. Incorporating a blend of …

Controllable membrane damage by tunable peptide aggregation with albumin

S Hamsici, G Gunay, H Acar - AIChE Journal, 2022 - Wiley Online Library
Aggregation of otherwise soluble proteins into amyloid structures is a hallmark of many
disorders, such as Alzheimer's and Parkinson's disease. There is an increasing evidence …

Peptide aggregation-induced immunogenic cell death in a breast cancer spheroid model

G Gunay, KN Maier, S Hamsici, F Carvalho, TA Timog… - bioRxiv, 2023 - biorxiv.org
Utilizing multicellular aggregates (spheroids) for in vitro cancer research offers a
physiologically relevant model that closely mirrors the intricate tumor microenvironment …